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Showing 1 to 12 of 12 for “"Versican"”.
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VALIDATION OF CANDIDATE GENES IN RESPONSE TO VERSICAN MANIPULATION IN DEVELOPING SYNOVIAL JOINTS
… early limb development. It has been shown that versican is highly expressed in the extracellular matrix of these joints (Snow et al., 2005; Shepard et al., 2007) and the knockdown of versican leads to malformation of the interzone, tissues that form the articular cartilage and synovial cavity …
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Left, Right, and Center: A Novel Midline Barrier Separates Asymmetric Extracellular Matrix During Intestinal Development
… pro-vascular, and bound to the proteoglycan versican. When these asymmetries and gut tilting are perturbed, the organism is at risk for volvulus, a catastrophic self-strangulation of the gut tube.The role of versican in gut morphogenesis is highly understudied, although it is known to be …
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Generating hair follicle inductive dermal papillae cells from adipose derived mesenchymal stem cells
… using RT-PCR showed that the DP-cell marker Versican is expressed at high levels in ASCs under routine culture conditions and the exposure of ASCs to Wnt results in a more than threefold increase in this expression. These results suggest that Wnt/β-catenin signalling may regulate DP cell …
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Knochenzellwachstum im dreidimensionalen Zellkultursystem
… Kollagen I und IV, Osteocalcin, Osteonectin, und Versican waren in den 3-D-Präparaten in allen Zeiträumen deutlich positiv, die Nachweise für Alkalische Phosphatase und Decorin negativ. Im Vergleich zu den 3-D-Kulturen war in der stimulierten 2-D-Kultur die Markierung von Osteocalcin deutlich …
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Βιοχημικές και ανοσοβιολογικές μεταβολές των πρωτεογλυκανών σε κακοήθη νεοπλάσματα του γαστρεντερικού συστήματος
… μόρια ανευρίσκονται στο παγκρεατικό καρκίνωμα, η versican και η decorin. Και οι δύο πρωτεογλυκάνες εντοπίστηκαν στο στρώμα και απουσίαζαν πλήρως από τα καρκινικά κύτταρα, γεγονός που υποστηρίζει ότι παράγονται από τις ινοβλάστες του στρώματος. Ήταν σημαντική η αύξηση των ποσοτήτων των δύο …
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Tissue repair in lung disorders
… extracellular matrix molecules such as collagen, versican, perlecan, biglycan, and decorin. Fibrocytes are recruited from the bone marrow to the site of injury. It is possible that the stromal cell-derived factor-1/CXCL12 builds up in a gradient to recruit CXCR4 expressing fibrocytes, at least in …
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Molekulare Zusammensetzung der extrazellulären Matrix im Patellar- und Quadrizepssehnenansatz frühkindlicher Patellae
… regelmäßig in den Anheftungszonen vor. Auch Versican und Tenascin sind stets in den Ansätzen zu finden. Link Protein lässt sich häufig in den Anheftungszonen nachweisen, während Aggrecan in rund zwei drittel der Fälle in der kindlichen Enthesis auftritt. Histomorphologisch stellt sich die …
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The ageing hair follicle environment. Alterations in the female scalp and mesenchyme with age.
… reduced podoplanin (PDPN) and increased versican (VCAN) expression. Hyaluronic acid synthase 2 (HAS2) was highly expressed throughout the scalp. Matrix Metallopeptidase 1 (MMP1) and Metallopeptidase inhibitor 1 (TIMP1), cyclin-dependent kinase inhibitor 2A (p16INK4A), 11β-Hydroxysteroid …
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Methamphetamine, interleukin-6 and perineuronal nets in synaptic plasticity
… of the G1 domains of two lecticans brevican and versican and used biochemical methods to characterize the valency of complexes and the kinetics of the binding affinities of lecticans and HA. The crystal structure, multimerization and relative binding affinities of the lecticans for HA suggest a …
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Charakterisierung von humanen mesenchymalen Stammzellen und Zellen der osteoblastären Differenzierungskaskade
… Abgrenzung differenzierter hOB. Die Proteine Versican und Matrixmetalloproteinase-2 erscheinen darüber hinaus für eine Unterscheidung von osteoblastären und fibroblastären Zellen nützlich zu sein. Die klassischen osteoblastären Marker alkalische Phosphatase, Kollagen-I, Osteopontin oder …
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The Role of Extracellular Matrix and Matrix-Degrading Proteases in Neonatal Hypoxic-Ischemic Injury
… in lesioned hippocampus. Additionally, reduced versican expression in white matter was concomitant with pre-OL cell death at this endpoint. In contrast, both lecticans were elevated at later endpoints (14, 21 days) that were associated with increased neuroinflammation and cavitary infarction. …