Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 18 of 18 for “"Vasodilators"”.
-
Studies of the cardiovascular effects of inotropic agents and vasodilators on the pulmonary and systemic circulation in man
Many drugs have recently been introduced for the treatment of hypertension and heart failure. These drugs may primarily affect the heart or components of the peripheral circulation and may have adverse as well as beneficial effects. Although animal studies can give some indication of the mode of …
-
Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
… our experience of the effects of treatment with vasodilators and oral anticoagulants, and the results of heart and lung transplantation in the PPH group; 3. Attempt to identify features which could be used to predict prognosis in PPH; and thereby 4. Define criteria for selecting PPH patients …
-
Implementing formulary recommendations in primary care: effect on patient outcomes.
… (UTIs), ulcer healing agents and peripheral vasodilators were selected for study, thereby reflecting both acute and chronic prescribing. For the UTI study, 12 randomly selected high and low prescribers of trimethoprim, the recommended agent, each agreed to distribute 20 patient …
-
Implementação de um sistema embarcado aplicado ao controle de pressão arterial
… as soon as possible. Continuous infusion of vasodilators drugs, such as sodium nitroprusside (SNP), rapidly decreased blood pressure in most patients, avoiding major problems. Maintaining the desired blood pressure requires constant monitoring of arterial blood pressure and frequently …
-
The Impact of Outward Remodeling on Vasodilation in Skeletal Muscle Resistance Arteries
… during outward remodeling, cell-dependent vasodilators were applied to the hindlimb. Endothelial- and smooth muscle-dependent vasodilation was significantly impaired 7 days post-ligation, but not 28 days after. This data supports the hypothesis that smooth muscle dysfunction causes impaired …
-
Fluid and blood pressure management in maintenance hemodialysis patients
… Because most blood pressure medications are vasodilators or impact other components of cardiovascular function, they may prevent the normal physiological response to changes in volume during dialysis, leading to intra- or inter-dialytic hypotension, post dialysis fatigue,[1, 2] and a reduced …
-
The vasodilatory and antioxidant activities of polyphenolic substances
… Grape based extracts were significantly better vasodilators than tea based extracts. Previous work by others has shown that grape based products induce vascular relaxation via nitric oxide (NO) and endothelium-dependent mechanisms. This study demonstrated that a range of grape based extracts …
-
Prostanoid-mediated Inhibition of IL-6 Trans-Signalling in Pulmonary Arterial Hypertension: a Role for Suppressor of Cytokine Signalling 3?
… Current treatment consists of a cocktail of vasodilators which relieve symptoms of PAH but do not treat the cause. Thus, there is a need for novel drugs that target the underlying pathological causes of PAH. PAH is a multi-factorial, but one key contributor is the pro-inflammatory cytokine …
-
Myocardial fibrosis and pathological hypertrophy in the rat with aorta-constricted hypertension
… to ANG I, including kinins (which are potent vasodilators); thus, the mechanism of ACE's action may be more complex than mere blockade of ANG II formation. To further distinguish the relative role of hemodynamic and humoral factors in promoting myocardial fibrosis, we used osmotic minipumps to …
-
Garlic and African olive used as traditional Herbs for hypertension in the Western Cape
… to severity using diuretics, beta-blockers, vasodilators in a stepwise progressive manner. In South Africa,traditional herbal medicines have been used to treat many ailments especially hypertension.Garlic and African olive has been reported as herbal medicines that have anti-hypertensive …
-
Garlic and African olive used as traditional Herbs for hypertension in the Western Cape
… to severity using diuretics, beta-blockers, vasodilators in a stepwise progressive manner. In South Africa,traditional herbal medicines have been used to treat many ailments especially hypertension.Garlic and African olive has been reported as herbal medicines that have anti-hypertensive …
-
Investigation of hypoxia and hyperglycaemia mediated DNA damage in human endothelial cells.
… derived molecules, such as nitric oxide, act as vasodilators as well as exhibiting anti-platelet, anti-proliferative, permeability decreasing and anti-inflammatory properties (Kawashima et al. 2004). Changes to the molecular processes or injury to the endothelium lead to endothelial dysfunction …
-
Relaxin: a new cardiovascular hormone in humans? Comparative potency and mechanisms of action
… potency of relaxin compared to other vasodilators: Small resistance arteries were obtained from biopsies taken from patients with CHD. Each set of vessels was preconstricted with noradrenaline. Thereafter, cumulative concentration response (relaxation) curves (CRCs) were constructed …
-
Die Regulation aktivierender und hemmender Signalwege in humanen neutrophilen Granulozyten durch cAMP- und cGMP-erhöhende Vasodilatatoren
Neutrophile Granulozyten sind wichtige Effektorzellen des menschlichen Immunsystems. Eine Suppression der Neutrophilen kann zur Immundeffizienz mit Gefahr für bakterielle Erkrankungen und maligne Tumoren führen, eine Überstimulation dieser Zellen ist jedoch an der Entstehung der …
-
Renal Epithelial Sodium Channel (ENaC) Regulation of Pregnancy Mediated Hemodynamic Adaptations: Mechanistic Insights
… from animals treated chronically with vasodilators (nifidipine or sodium nitrate). We found that only the abundance of transporters in the distal nephron (NCC, ENaC, AQP2) was similar to pregnancy, however differences were seen in pre-macula densa transporters (NHE3, NKCC2). The similar …
-
Protein Trafficking of BK Channel β1 Subunits in Cerebral Artery Myocytes
… high myogenic tone and are less responsive to vasodilators, including nitric oxide (NO). The regulation of arterial contractility by BK channels is altered during hypertension, although mechanisms involved are also unclear. </p> <p><strong>Objective: </strong>Test the hypothesis that ET-1 …
-
Metabolic regulation of human vascular endothelial cell function in vitro
… are mediated through coordinated release of vasodilators such as nitric oxide (NO) and prostacyclin, and vasoconstrictors such as endothelin-1 and thromboxane A2. Endothelial NO is the principal vasodilator in the vasculature and is produced by endothelial nitric oxide synthase (eNOS). …
-
The roles of O₂, H⁺, and K⁺ in skeletal muscle functional vasodilation
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).