Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 72 for “"Vasoconstriction"”.
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Cellular mechanisms of acute hypoxic pulmonary vasoconstriction in intrapulmonary veins.
… to blood flow regulation. Hypoxic pulmonary vasoconstriction (HPV) involves both pulmonary arteries and veins, but little is known of the contractile mechanisms specific to the veins. The aim of these studies was to examine the hypoxic response in small porcine intrapulmonary veins in …
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Molecular Mechanisms Underlying Alcohol-Induced Cerebral Artery Smooth Muscle BK Channel Inhibition and Eventual Cerebral Vasoconstriction
… during binge drinking (30-60 mM) causes cerebral vasoconstriction in many species, including humans. Using rodents as a model to study ethanolinduced cerebral artery constriction, our laboratory demonstrated that ethanol-induced cerebral artery constriction is due to drug-induced reduction of …
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Muscle Metaboreflex And Arterial Baroreflex: Action, Interaction And Altered Control In Heart Failure
… from which this reflex originates and if this vasoconstriction is exaggerated in heart failure and 3) how do the arterial baroreflex and muscle metaboreflex interact with each other when activated simultaneously in normal and heart failure animals. Using chronically instrumented canine model, …
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Rôle modulateur de l'oxyde nitrique dans la vasoconstriction et l'élévation du calcium intracellulaire induites par l'endothéline-1 et le thromboxane A[indice inférieur 2] dans des vaisseaux humains et de lapins
L'endothélium vasculaire sécrète une variété de substances constrictrices comme l'endothéline-1 (ET-1) et le thromboxane A[indice inférieur 2] (TXA[indice inférieur 2]), ainsi que des substances relaxantes tel l'oxyde nitrique (NO). Ces facteurs sont importants dans la modulation du tonus …
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The role of spontaneous bursts of muscle sympathetic nerve activity in mediating peripheral vascular responses and cardiovascular hemodynamics in resting man
… sympathetic nerve activity to dynamically evoke vasoconstriction is paramount for the regulation of blood flow and blood pressure. However, very little information is available to characterize the influence of spontaneously occurring sympathetic nerve activity on human blood vessels during rest. …
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Exercise Training Improves Cerebrovascular Oxidative Stress Regulation and Insulin Stimulated Vasodilation in Juvenile and Mature Pigs
… cerebrovasculature, characterized by augmented vasoconstriction in response to insulin, may relate to enhanced sensitivity to endothelin-1 (ET1) or increased oxidative stress, culminating in attenuated nitric oxide (NO) signalling. Regular exercise has been shown to enhance vascular responses to …
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Muscle Metaboreflex Control Of Coronary Blood Flow And Ventricular Contractility During Dynamic Exercise In Normal And Heart Failure Conditions
… to concomitant sympathetically induced coronary vasoconstriction. In heart failure, cardiac output does not increase with MMA presumably due to impaired left ventricular contractility, and large decreases in coronary vascular conductance are observed. The purpose of this dissertation is to …
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Neural And Humoral Control Of Regional Vascular Beds Via A1 Adenosine Receptors Located In The Nucleus Of The Solitary Tract
… with</p> <p>sympathetic and unknown humoral vasoconstriction. Among many potential</p> <p>vasoconstrictors vasopressin, angiotensin II and circulating norepinephrine were</p> <p>considered. Therefore, blood pressure and iliac vascular responses evoked by</p> <p>selective stimulation of NTS …
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Photoplethysmography for non-invasive measurement of bone hemodynamic responses to changes in external pressure
… wide range of pressure levels. Myogenic-induced vasoconstriction is observed at all negative pressure levels, with increasing vasoconstriction at the more extreme pressure differences. At positive pressures we observed an initial myogenic-induced vasodilation followed by activation of the …
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Muscle Metaboreflex Control Of Cardiovascular Function In Hypertension
… occurs via increased CO with no net peripheral vasoconstriction. When metaboreflex activation is sustained during the recovery from exercise (i.e., post-exercise muscle ischemia - (PEMI)), whereas MAP remains elevated for as long as the ischemia is maintained, HR precipitously declines towards …
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Vascular Mechanisms of Rhabdomyolysis-induced Acute Kidney Injury
… direct kidney injury as well as severe renal vasoconstriction. An increase in renal vascular resistance (RVR) results in renal blood flow (RBF) and glomerular filtration rate (GFR) reduction, tubular injury, and acute kidney injury (AKI). The mechanisms that underlie rhabdomyolysis-induced AKI …
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Hallucinogens: a Cause of Convulsive Ergot Psychoses
<p>Ergotism with vasoconstriction and gangrene has been reported through the centuries. Less well publicized are the cases of psychoses associated with convulsive ergotism. Lysergic acid amide a powerful hallucinogen having one.-tenth the hallucinogenic activity of LSD-25 is produced by natural …
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In vivo investigations of photoplethysmograms and arterial oxygen saturation from the auditory canal in conditions of compromised peripheral perfusion
… perfusion such as hypotension, hypothermia, and vasoconstriction, the PPG signals detected are often small and noisy, or in some cases unobtainable. Hence, pulse oximeters produce erroneous SpO2 readings in these circumstances. The problem arises as most commercial pulse oximeter probes are …
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Molecular and cellular mechanisms implicated in the regulation of cellular PMCA expression during pulmonary arterial hypertension
… current cure and available therapies alleviate vasoconstriction but do not address the disorder associated vascular remodelling. Amplified activity of pro-inflammatory cytokines has been linked to PAH development and progression. The aberrant re-modelling of the vasculature is in part dependent …
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Mechanisms of Control of Blood Flow in the Forelimb of Sheep
… response.</p> <p>Norepinephrine produces a rapid vasoconstriction and decrease in flow. There is a slight recovery during the infusion. The recovery takes several minutes and it is without overshoot. The response to epinephrine is diphasic. During the first minute there is a vasodilation and …
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Signal Transduction Mechanisms Mediating the Regulation of Vascular G Protein-Coupled Receptors
… between mechanisms regulating vasodilatation and vasoconstriction. The extensive loss of GRK2 expression favors an increased in vasoconstriction associated with an increase in peripheral resistance and this is likely due to the reduced Gαq/11-coupled receptor desensitization. The vasodilatation in …
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The effects of bradykinin and angiotensin II on the thoracic aorta vasa sasorum microcirculation system
… two important vasoactive peptides, which produce vasoconstriction and vasodilatation, respectively. They can also change the permeability of microcirculation. In the present study, we documented the effect of different concentrations of ANG II and bradykinin on the vasa vasorum of isolated rabbit …
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Role of conceptus-induced vasodilation in controlling utero-ovarian function of ewes, cows and sows
… UA from FP and P gilts ahd reduced (P < 0.01) vasoconstriction in vitro compared with UA from LP gilts, (alpha)-adrenergic receptor levels were reduced (P < 0.05) only for UA from FP and not P gilts compared with LP gilts. Experiment II: As observed for UA in experiment I, vasoconstriction of …
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Interactions between potassium channels and serotonin in pulmonary arterial hypertension
… disease process and is thought to promote both vasoconstriction and remodelling of the pulmonary vasculature. The activity of potassium ion (K+) channels plays a major role in influencing pulmonary artery tone by regulating resting membrane potential, intracellular Ca2+ concentration and …
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Cardiovascular and respiratory reflex control systems in the regulation of pulmonary blood flow and ventilation during exercise
… of the muscle metaboreflex induced pulmonary vasoconstriction that was alleviated by muscle mechanoreflex activation. Furthermore a respiratory response to the activation of the muscle metaboreflex was observed in hypercapnia but not when breathing room air. Finally we found that increases in …
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