Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 61 for “"Vascular resistance"”.
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Effects of Early Cirrhosis on Hepatic Vascular Resistance in the Rat
The Problem. Increased vascular resistance in the liver is a common symptom of established cirrhosis of the liver. This investigation measured changes in resistance during induction of cirrhosis, to determine whether the increase in vascular resistance might be part of the mechanism by which …
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Feto-placental vascular structure and function: comparison of within and between species variations
… differences in human and rodent fetoplacental vascularisation. This thesis is motivated by a need to understand species differences, as despite promising therapies for pregnancy complications in animal models, clinical effectiveness is limited due to differences in placental structure and …
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A Combined In Vivo and In Vitro Approach to the Study of Endotoxemia in Swine
… in mean pulmonary artery pressure, pulmonary vascular resistance, pulmonary arterial wedge pressure, heart rate, hematocrit, and the arterial partial pressure of carbon dioxide. Transient increases were also observed in central venous pressure and airway pressure. Transient increases, followed …
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The Acute And Chronic Effects Of Resveratrol On Renal Function And Blood Pressure
… increasing renal blood flow and decreasing renal vascular resistance. The mechanism of renal vasodilation was nitric oxide dependent and through a reduction of endogenous reactive oxygen species. Resveratrol-induced renal vasodilation was not influenced by COX metabolism and vasodilatory …
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Preeclampsia Link to Gestational Hypoxia
… remodelling and resulting in increased placental vascular resistance, reduced uteroplacental perfusion, triggering placental hypoxia and oxidative stress. In turn, placental dysfunction is thought to be a common denominator between upstream adverse effects on the mother and downstream adverse …
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Effects of organophosphate esters on blood vessels: a physiological, pharmacological, and histological assessment of involvement in organophosphorus-induced delayed neuropathy (OPIDN)
The contribution of the cardiovascular system. to organophosphate-induced delayed neuropathy (OPIDN) was examined using in situ and in vitro models for demonstration of response to vasoactive agents (e.g., the cholinergic agonist, acetylcholine; the α1 agonist, phenylephrine; and the β2 agonist, …
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Controlled cross circulation: effects on donor hemodynamics
… capillary wedge pressure, blood volume, systemic vascular resistance, heart rate, total protein, platelet count, and white blood cell count did not change significantly. Donor cardiac output, end diastolic volume, central venous pressure, stroke volume, mean arterial blood pressure, and packed …
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Investigating Hemodynamic Responses to Electrical Neurostimulation
… the number of deaths attributable to cardiovascular disease has steadily risen. With the advent of antihypertensive drugs and non-invasive surgical procedures, such as intravascular stenting, these numbers have begun to level off. Despite this trend, the number of patients diagnosed with …
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Single Nucleotide Polymorphisms of the ATP1a2 gene and Their Effects on Blood Pressure and Other Cardiovascular Variable in African Americans and Caucasian Americans
… Their Effects on Blood Pressure and Other Cardiovascular Variables in African Americans and Caucasian Americans. Doctor of Philosophy (Integrative Physiology), May 2007. Mutations in the 3’ – untranslated region (3’-UTR) of the ATP1a2 gene, which encodes the α2 subunit of Na+-K+-ATPases are …
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Validation of a new method of determining cardiac output in neonatal foals
… increased cardiac output and decreased systemic vascular resistance. In the first instance, treatment would include fluids and/or inotropes and in the second, fluids and/or vasopressors. Therefore, cardiac output measurements are expected to help guide the treatment of hypotension associated with …
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Evaluation of metabolic and cardiovascular actions of [Pyr1]apelin-13 in patients with Type 2 diabetes mellitus
… Thesis title: Evaluation of metabolic and cardiovascular actions of [Pyr1]apelin-13 in patients with Type 2 diabetes mellitus Type 2 diabetes mellitus (T2DM) is common, long term metabolic disorder characterised by hyperglycaemia (high blood glucose) resulting from insulin resistance (IR) and …
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Αιμοδυναμικές και αναπνευστικές επιδράσεις της θειϊκής πρωταμίνης σε σχέση με την οδό και τον ρυθμό χορήγησης: Πειραματική μελέτη
… of cardiac output, measurement of pulmonary vascular pressures and sampling of mixed venous blood. Through the ventilatory circuit, end-tidal CO₂ and compliance were continuously monitored with Analyzer CO₂ 930-Siemens and Lung mechanics calculator 940-Siemens. ECG monitoring, all pressures …
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The bone cement implantation syndrome - epidemiology, pathophysiology and prevention
… We observed a 45% increase in the pulmonary vascular resistance index (PVRI) for patients who were undergoing cemented hemiarthroplasty for femoral neck fracture, and this was accompanied by significant decreases in the right ventricle ejection fraction (RVEF), cardiac index (CI), and stroke …
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Laboratory Development of a Self-Powered Fontan for Treatment of Congenital Heart Disease
… Needle valves are used to accurately replicate vascular resistance (R) while compliance chambers are used to mimic vascular compliance values (C). The Fontan MFL is driven with cardiac pulsatility provided by a Harvard Apparatus medical pump. Patient-specific models of the centerpiece of the MFL …
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Tracking autonomic balance using open and closed loop models of the arterial baroreflex
… homeostasis by dynamically adjusting heart rate, vascular resistance, venous tone, and cardiac contractility. Accurate quantitative models of the baroreflex would provide physiological insight, and could allow for real-time tracking of ANS activity in clinical settings. Prior work has concentrated …
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The Effects of Dendro[60]Fullerene on Neurobehavioral Outcome and Cerebral Vascular Function After Traumatic Brain Injury
… oxygen species (ROS) that leads to cerebral vascular dysfunction. The reduction of ROS can preserve vascular function and lead to improved outcomes. The antioxidant carboxyfullerene nanoparticle, dendro[60]fullerene (DF-1) was examined as a potential therapy for TBI because of its strong …
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Valutazione degli aggiustamenti cardiocircolatori durante apnea statica e dinamica in apneisti d'elitè mediante l'uso di un dispositivo portatile
… elicited by the diving response. However, cardiovascular measurements have never been performed during underwater dynamic apnoea (DA), and this hypothesis remains speculative. Methods: Data concerning heart rate (HR), stroke volume (SV) and cardiac output (CO) during static apnoea (SA) and DA …
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Effekte des intraabdominellen Drucks auf respiratorische Parameter und den Gasaustausch unter druckkontrollierter versus assistierter Beatmung mit BIPAP
… superior respiratory mechanics and cardiovascular stability as compared to BIPAPPC. Although the decrease of dynamic compliance and the increase of airway pressures were mitigated, BIPAPSB failed to lower pulmonary vascular resistance and caused increased dead space ventilation (p=0.007). …
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Etablierung eines modifizierten Adriamycin-induzierten Herzinsuffizienzmodells am Schwein
… pulmonary wedge pressure, and pulmonary vascular resistance, whereas cardiac output, stroke volume index, and left ventricular stroke work index decreased. These results were supported by the echocardiographic data depicting an increase of left ventricular diameters and volumes, …
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