Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Vascular morphology"”.
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Quantitative Analysis of Retinal Vascular Morphology and Dynamics Using Optical Coherence Tomography
… and validation of OCT methods for quantitative vascular analysis. We introduced depth-resolved vascular profile analysis for artery-vein classification, identifying wall boundary patterns and lumen intensity features from B-scans. These features enabled robust vessel type identification in the …
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The effect of brain-specific VEGF-C deletion on vascular morphology in the brain and skull
Vascular endothelial growth factor C (VEGF-C) promotes mainly lymphangiogenesis, but it can also stimulate angiogenesis by binding to VEGFR3 and VEGFR2 on endothelial cell surface. We studied VEGF-C expression by β-galactosidase staining in VegfcLacZ/+ mice. This revealed Vegfc expression in …
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Contrast-enhanced Doppler Ultrasound Imaging using Plane Waves
… would be capable of displaying perfusion and vascular imaging simultaneously. In ultrasound, Doppler can visualize veins and arteries, but cannot detect the capillary level perfusion. Conversely, microbubble contrast-enhanced ultrasound imaging enables low velocity perfusion to be detected and …
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Intracranial Vascular Findings in a Tri-Ethnic Population – MR Phenotypes and Physiological Parameters
… in-depth, detailed knowledge of the intracranial vascular anatomy and cerebrovascular physiology is ultimately essential for accurate diagnosis and therapy. With the emerging availability of medical imaging and rapid technological advances, in particular concerning non-ionising magnetic resonance …
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Pericytes in Early Vascular Development
… and pericytes during development, we observed vascular morphology in three and four dimensions, as well as the genetic and molecular mechanisms underlying how these cells are recruited and interact in several experimental models. Thus, to thoroughly analyze the morphology of these vessels, we …
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Effects of organophosphate esters on blood vessels: a physiological, pharmacological, and histological assessment of involvement in organophosphorus-induced delayed neuropathy (OPIDN)
The contribution of the cardiovascular system. to organophosphate-induced delayed neuropathy (OPIDN) was examined using in situ and in vitro models for demonstration of response to vasoactive agents (e.g., the cholinergic agonist, acetylcholine; the α1 agonist, phenylephrine; and the β2 agonist, …
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Role of ANLN in post ischaemic angiogenesis
… develop new therapeutic strategies for cardiovascular disease. One such gene identified in the Caporali lab is Anillin (ANLN) an F-actin binding protein with functions in cytokinesis, asymmetric cell division and potential roles in migration and proliferation in multiple cell types. We …
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Characterization of the expression of angiogenic factors in the feline placenta during development and in feline cutaneous squamous cell carcinoma
… junctional, and glandular zones, each with a vascular morphology attuned to its function. We hypothesized that higher expression of pro-angiogenic factors is associated with increased morphological metrics in the LZ, the major vascularized zone. Thus, we aimed to characterize the major changes …
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Drug Delivery and Anti-Vascular Effects of Temperature Sensitive Liposomal Doxorubicin
… drug concentration in the tumor, and an anti-vascular effect not observed with heat alone. These initial studies have also suggested that these liposomes may be the most efficacious when they are injected into a pre-heated tumor, with the hypothesis that in this treatment scheme the liposomes …
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Multi-modal molecular imaging of radiation therapy response in the tumour vascular microenvironment
… therapy based on changes in the tumour vascular architecture and blood oxygen saturation, which are closely linked to tumour hypoxia. Given the strong relationship between hypoxia and radioresistance, PAI assessment of the tumour vascular microenvironment has the potential to detect …