Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 227 for “"Vascular Endothelial Growth Factor"”.
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Anti-vascular endothelial growth factor in ophthalmology
Vascular endothelial growth factor, secreted by the neurovascular retina, acts as an essential regulator in vasculogenesis, angiogenesis, and increased vascular permeability, which plays a critical role in the pathophysiology of ischemia-related retinal illnesses, inducing aberrant …
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Vascular Endothelial Growth Factor In Cortical Development
… each other and intimately linked.</p> <p>Many growth factors and transcription factors have roles in both angiogenesis and neurogenesis. Members of both the Notch and Inhibitor of DNA binding (Id) family of proteins have been shown to guide differentiation in neural stem cells, as well as to …
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Experimental estimate of the diffusivity of Vascular Endothelial Growth Factor
The diffusivity of Vascular Endothelial Growth Factor (VEGF) is a number that is very important in determining the transport of VEGF. The transport of VEGF determines crucial processes such as angiogenesis and vasculogenesis. This study aimed at obtaining an estimate of the diffusivity of VEGF by …
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Expression of Vascular Endothelial Growth Factor(VEGF), Vascular Endothelial Growth Factor Receptor-1(VEGFR-1), Hypoxic Induced Factor-1alpha(HIF-1α) mRNA in Papillary Thyroid Microcarcinoma(PTMC)
… Angiogeneisis is essential process for tumor growth and metastasis. Vascular endothelial growth factor(VEGF) is major regulator of angiogenesis. Recently, the incidence of papillary thyroid microcarcinoma(PTMC) increased because of development in diagnostic modality. Several recent reports …
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The role of vascular endothelial growth factor isoforms in early follicle development
Since vascularization of the theca layer increases as follicles progress in size through preantral and antral stages, the principal angiogenic factor, vascular endothelial growth factor A (VEGFA), may influence follicle growth via regulation of angiogenesis. However, VEGFA may also influence …
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Charakterisierung von Knochenmark-generierten Makrophagen unter der Einwirkung von Vascular Endothelial Growth Factor
… von BMDM unter dem Einfluss von Vascular endothelial growth factor (VEGF). Durch die Beteiligung von Monozyten/ Makrophagen an arteriogenen Prozessen, ist eine indirekte pro-arteriogene Wirkung von VEGF über Beeinflussung der Monozyten/Makrophagen vorstellbar. Die vorliegende …
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Vascular Endothelial Growth Factor in the Aqueous Humor of Dogs With and Without Intraocular Disease
Vascular endothelial growth factor A (VEGF) is a potent mediator of blood vessel formation throughout the body. Intraocular diseases characterized by inflammation, hypoxia or neoplasia induce new blood vessel formation within the eye. The end result of such blood vessel formation may be blinding …
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Modeling of interactions between vascular endothelial growth factor family members and their receptors KDR and Flt-1
The vascular endothelial growth factor (VEGF) family is prominently involved in angiogenesis, the formation of new vasculature. Overexpression has been linked to pathological conditions including solid tumor growth. Responses to VEGF are mediated by Flt-1 and KDR, two cell-surface receptors …
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Expression of Vascular Endothelial Growth Factor-A and its Receptors in Uteroplacental Tissues of the Normotensive and Hypertensive Pregnant Rat
… leading to preeclampsia and fetal intrauterine growth retardation. Many studies have shown that vascular endothelial growth factor A (VEGF-A) is a potent angiogenic factor, that is, it is responsible for the formation of new blood vessels from existing vessels. VEGF-A has been shown to be …
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Cyclic stretch-mediated release of vascular endothelial growth factor by vascular smooth muscle cells : a role in improved vascular graft patency
… phosphorylation in response to cyclic stretch in vascular cells, the effect of cyclic strain on the KDR-mediated endothelial response to locally-released VEGF was also investigated. Low passage number bovine aortic SMC and EC were plated on collagen-coated elastomer plates and subjected to 10% …
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Expression von VEGF (vascular endothelial growth factor) beim Urothelkarzinom der Harnblase - eine vergleichende Untersuchung histologischer Präparate nach Transurethraler Resektion und nach Cystektomie
… klinische Verläufe zeigen können. Der VEGF (Vascular Endothelial Growth Factor) wurde als wichtiger angiogenese-stimulierender Mediator beim Harnblasenkarzinom identifiziert. Bisher konnte zeigt werden, dass die Expression von VEGF im Harnblasenkarzinom gegenüber unauffälligem Blasengewebe …
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Analysis of the expression and effects of vascular endothelial growth factor family of molecules on Fragile X Syndrome abnormalities in a mouse model
… have all failed, attributing to various factors such as a need for optimized dosage, developmental time for intervention, better metrics for human studies, and most prominently complexity of the mGluR pathway (Scharf et al., 2015). With this ubiquitous failure of mGluR inhibitors, new …
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Einfluss von vascular endothelial growth factor, transforming growth factor-beta-1, Interleukin-6, atrial natriuretic beptide, brain natriuretic peptide und Cortisol auf die Gen-Expression des menschlichen Herzmuskels in vitro
Die vorliegende Arbeit untersucht die Effekte von Vascular Endothelial Growth Factor (VEGF), Transforming Growth Factor-beta-1(TGF-beta-1), Interleukin-6 (IL-6), Atrial Natriuretic Peptide (ANP), Brain Natriuretic Peptide (BNP) und Cortisol (bzw. Dexamethason) auf das humane Myokard. Um …
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Diabetic macular oedema: the role of steroids and VEGF
… and increase visual acuity in the long-term. Vascular endothelial growth factor is thought to play a critical role during the pathogenesis of diabetic macular oedema. The mechanism of action of both steroids and vascular endothelial growth factor on permeability has still to be fully …
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Sub threshold high frequency electrical field stimulation effect for angiogenesis and vegf expression in cardiomyocytes and heart tissue. Remodelling in the heart: impact of mechanical stretch, threshold and sub-threshold electrical stimulation on cultivated cardiomyocytes and sympathetic neurons /
To evaluate growth factors response to various stimulation techniques in the field of neurocardiology. This research asses the influence of electric field and stretching effect on biologically active proteins. In this work the following research tasks are answered: To investigate the effect of sub …
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The retinal microvasculature as an early indicator of chronic disease risk in older populations
… of chronic systemic diseases with a vascular component. This easy, non-invasive imaging modality provides an indication of microvascular health that may reflect ongoing changes elsewhere in the body. The current published literature provides conflicting evidence on the associations …
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Novel mechanisms for buffering the haemodynamic effects of dietary salt and the relevance of skin sodium in humans
… United Kingdom and it remains an important risk factor for cardiovascular morbidity and mortality. Dietary sodium is an important trigger for hypertension and humans show a heterogeneous blood pressure (BP) response to salt intake. The mechanisms for this have not been fully explained, with renal …
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