Global ETD Search
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Showing 1 to 2 of 2 for “"Variable New Antigen Receptors"”.
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Transdermal delivery of heavy chain only antibody binding domains using hydrogel-forming microarray patches
… stability limitations associated with mAbs. This new era of biotechnology incorporates heavy chain only antibodies (HCAbs) such as Nanobody® molecules and VNARs, derived from camelids and sharks, respectively. Owing to their small size (~13 kDa) and reduced complexity, they are less expensive to …
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Development of novel polymeric nanoparticles for pancreatic cancer therapy
… shark-derived immunoglobulin fragments known as Variable New Antigenic Receptors (VNARs) to the surface of polymeric NPs. This is a novel use of VNARs for which they have many advantageous properties including high physicochemical stability, small size, and low chemical complexity while still …