Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"VapBC"”.
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The Biochemistry of VapBC Toxin-Antitoxins
The VapBC toxin-antitoxin (TA) systems were first identified in 2005 and little is known about their contemporary biological function, despite the fact that VapBC TAs are the largest TA family and are widespread in bacteria and archaea (Arcus, Rainey, & Turner, 2005; Gerdes, Christensen, & …
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Regulation of Metabolism in Mycobacteria and Cyanobacteria
… characterisation of a previously unexplored VapBC family of Type II Toxin Antitoxin (TA) systems found in the cyanobacteria Microcystis aeruginosa and Synechocystis sp. PCC6803 (Synechocystis). Investigation of the biochemistry of M. aeruginosa VapBC systems was limited by poor expression, …
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Functional Genomics of Stress Response in the Hyperthermophilic Crenarchaeon Sufolobus solfataricus and Role of vapBC Toxin-Antitoxin Loci in RNA Management.
… stress. In addition, 10 ORFs belonging to vapBC Toxin-Antitoxin (TA) loci were also implicated in the stress response of this archaeon. In silico analysis of the structural features of S. solfataricus two VapC toxins was conducted to examine the putative roles of Toxin-Antitoxin (TA) …
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Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control
… and virulent endemic Rangipo strain. The role of VapBC toxin-antitoxin systems in M. tuberculosis has been the subject of great interest recently, due to their expanded number in the genome and links with virulence and the regulation of cell growth in response to environmental stress. Their …
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The Biology and Biochemistry of PhoH2 proteins
… that comprise the toxic component (VapC) of VapBC toxin antitoxin systems, in which the PIN domain is coexpressed as part of an operon with an inhibitor (VapB). In the remaining cases where PIN domain proteins can be found such as PIN PhoH domain fusions, these cases remain unexamined. This …