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Showing 1 to 20 of 148 for “"Vancomycin"”.
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Characterization of Vancomycin Resistance in Staphylococcus Aureus
… Staphylococcus aureus has developed two distinct vancomycin resistance mechanisms. First, the bacterium is capable of generating a thickened, poorly crosslinked cell wall that creates false targets. These targets cause vancomycin to bind at the periphery of the thickened peptidoglycan, allowing …
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Mechanistic Insights Into Vancomycin Resistance In Clostridioides Difficile
… become more hypervirulent over the last decade. Vancomycin is currently a frontline antibiotic for the treatment of <em>C. difficile</em> infections. Yet, strains of <em>C. difficile</em> are becoming non-susceptible to vancomycin. Emergence of the vancomycin non-susceptible phenotype has led to …
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Design and synthesis of modified peptide antibiotics of the vancomycin family
… and S. Aureus that show resistance to vancomycin is an alarming phenomenon, as vancomycin represents the last line of defence against pathogens with a significant level of resistance to all other available therapies, methicillin resistant S. Aureius (MRSA) being a prime example of such …
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Characterization of Metronidazole- and Vancomycin-Resistant Clinical Isolates of Clostridium Difficile
<p><strong>Characterization of Metronidazole- and Vancomycin-Resistant Clinical Isolates of <em>Clostridium difficile</em></strong></p> <p>Chioma Odo, MS.</p> <p>Supervisory Professor: Charles Darkoh, Ph.D.</p> <p><strong>ABSTRACT</strong></p> <p>The incidence of <em>C. difficile</em> infections …
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Optimal Control Applied to a Mathematical Model for Vancomycin-Resistant Enterococci
… be treated effectively with the antibiotic vancomycin are termed Vancomycin-Resistant Enterococci (VRE). In this thesis, we develop a mathematical framework for determining optimal strategies for prevention and treatment of VRE in an Intensive Care Unit (ICU). A system of ve ordinary …
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Rectal culture screening for vancomycin-resistant enterococcus in chronic haemodialysis patients
Infection or colonisation with vancomycin-resistant enterococci (VRE) is common in chronic haemodialysis(HD) patients. However, there is limited information on the duration of VRE colonisation or on the reliability of consecutive negative rectal cultures to determine the clearance of VRE in chronic …
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Molecular Characterization of Vancomycin-resistant Enterococci from Clinical and Surveillance Specimens
BACKGROUND: Vancomycin-resistant enterococci(VRE) were first detected in Europe in 1986, and have been isolated from hospitalized patients worldwide. VanA resistance, characterized by high level resistance to vancomycin and teicoplanin, is the most prevalent in clinical enterococcal isolates. To …
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Repurposing Antibacterial Compounds and Natural Products to Combat Vancomycin-Resistant Enterococci
… Among the most concerning pathogens are vancomycin-resistant Enterococcus (VRE), which causes serious bloodstream, urinary tract, and wound infections, particularly in hospitalized patients. This thesis explores two complementary strategies to address this challenge: natural product …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… to glycopeptide antibiotics, especially Vancomycin is of special concern as Vancomycin resistant genes are encoded on plasmids which can be transferred to other organisms. Currently, there is no documented information relating to the occurrence and resistance genes of VRE at the …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… to glycopeptide antibiotics, especially Vancomycin is of special concern as Vancomycin resistant genes are encoded on plasmids which can be transferred to other organisms. Currently, there is no documented information relating to the occurrence and resistance genes of VRE at the …
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Development of dissolving and hydrogel-forming microneedles for delivery of vancomycin hydrochloride
… deadly infections, including neonatal sepsis. Vancomycin, a glycopeptide antibiotic, remains the most effective antibiotic to treat this condition. In the case of systemic diseases, vancomycin must be administered via intravenous injection. However, administration of vancomycin via this route …
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I. Transannular Sulfoxide - Ketone Interaction. Ii. A Prospectus of the Vancomycin Structure
Made available in DSpace on 2014-12-05T19:38:02Z (GMT). No. of bitstreams: 1 6206166.pdf: 4399515 bytes, checksum: c7ff8da0afe1b70c28dc46e03a1d12fa (MD5) Previous issue date: 1962
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Library Screening and Focused Multiomics of Antibacterial Action on Vancomycin-Resistant Enterococci faecium
… the gastrointestinal tract and the soft tissues. Vancomycin has been one of most important agents for the treatment of gram-positive bacterial infections. The emergence and spread of vancomycin resistance has become a serious public health issue and vancomycin resistant bacteria are world’s …
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Some Properties of Vancomycin in Relation to Its Absorption and Movement in Plants
Made available in DSpace on 2014-12-05T20:30:08Z (GMT). No. of bitstreams: 1 0025253.pdf: 4409449 bytes, checksum: 836c6c5a9f4305486875560d04a18dd9 (MD5) Previous issue date: 1957
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A genome wide approach to identify factors asociated with vancomycin non-susceptibility in Staphylococus aureus
Vancomycin (VAN) represents the standard of care in the treatment of Methicillin-Resistant S. aureus (MRSA) infections and widespread use has driven antimicrobial resistance. While fully resistant S. aureus strains have been identified, vancomycin-intermediate S. aureus (VISA) and heterogeneous …
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The effects of oligosaccharides and probiotic bacteria on the intestinal microflora and vancomycin-resistant enterococcus
… of probiotic bacteria on the suppression of vancomycin-resistant enterococcus in vitro.
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A genome wide approach to identify factors asociated with vancomycin non-susceptibility in Staphylococus aureus
Vancomycin (VAN) represents the standard of care in the treatment of Methicillin-Resistant S. aureus (MRSA) infections and widespread use has driven antimicrobial resistance. While fully resistant S. aureus strains have been identified, vancomycin-intermediate S. aureus (VISA) and heterogeneous …
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