Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Vaginal microbicide"”.
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MABGEL 1: C2F5, C4E10 & C2G12 as a vaginal microbicide
Topical microbicides are being developed as a female-controlled method for preventing HIV-1 infection. Non-antiretroviral (ARV)-based candidates may be advantageous given increasing levels of ARV resistance in low and middle- income countries.MABGEL 1 was a phase 1 trial designed to evaluate the …
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Research on the epidemiology and prevention of HIV in rural south west Uganda, 1989-2010
… trials (of STDlbehaviour change and a phase 3 vaginal microbicide) are also discussed. Neither trial showed any effect on HIV transmission. To explain the findings from these trials, a conceptual framework for discussing negative results from HIV prevention trials has been used. The possible …
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Pig mucus as an inhibitory agent of HIV-1
… for anti-HIV-1 research. Pig gastric and cervico-vaginal mucus was collected and stirred overnight in 6M guanidine hydrochloride with 10mM Na₂HPO4, 10mM EDTA, 1mM PMSF and 5mM NEM. Gastric and cervicovaginal mucus was purified by density gradient ultracentrifugations in CsCl at 105 000g for 48 …
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IN VITRO SUSCEPTIBILITY OF CHLAMYDIA TRACHOMATIS TO LPS-BINDING POLYAMINES AND CELLULOSE ETHER POLYMERS: TOWARDS THE DEVELOPMENT OF A MICROBICIDE AGAINST CHLAMYDIA INFECTION
… vaccine, my study focused on development of a vaginally-delivered topical microbicide as an alternative strategy for prevention of Chlamydia. The paucity of a well-established method suitable for large-scale analysis of in vitro Chlamydia infection is a major limitation in the development of …
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Formulation of Hyaluronidase Enzyme Sensitive Topical Nanomicrobicides for HIV Virus Transmission Prevention
… delivery system loaded with anti-HIV topical microbicides for HIV prevention in women. In chapters 1 and 2, the overview of the problem, research objectives as well as the literature review of the technical and scientific background of this dissertation are introduced. In chapter 3, a study …