Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Vaginal Tissue"”.
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Time-dependent deformations of vaginal tissue: Experiments and constitutive modeling
… gaps in knowledge on the creep properties of vaginal tissue. In our first study, we subjected rat vaginal canals to three consecutive creep tests, each at progressively increasing constant luminal pressures, without recovery, and measured the resulting deformations using the digital image …
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Tearing of Vaginal Tissue under Biaxial Loading: Implications for Women's Health
Around 80% of women experience vaginal tears during labor when the diameter of the vagina must increase from ~2.5 cm to ~9.5 cm to allow the passage of a full-term baby. Vaginal tears vary from superficial cuts of the mucosal lining to tears propagating through the entire vaginal wall and into the …
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Immunohistochemical analysis of a panel of human and murine markers on xenografted human vaginal mucosa: a comparative study
… behaviour of normal and diseased human tissues. In such models, immune-deficient mice act as hosts for cysts constructed from human material. A unique biocyst model that entails transplantation of human vaginal cysts into athymic nude mice has been implemented to study diseases of oral …
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Advancing Maternal Health through Projection-based and Machine Learning Strategies for Reduced Order Modeling
… displacement fields of rat vaginal tissue during inflation testing in order to attain both the accuracy of higher-fidelity models and the speed of lower-fidelity simulations. The proper orthogonal decomposition (POD) method was used to extract the significant information from …
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Exposure of 3D organotypic vaginal tissues to semen induces expression of the chemokine MCP-1, but does not alter tissue integrity
… that human semen induces inflammatory changes in vaginal epithelial cell cultures, which may promote HIV transmission. Since the normal human vagina is differentiated into multiple cell layers, we conducted a study to determine the effect of semen on EpiVaginal™, a 3-D organotypic differentiated …
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Zearalenone contamination in swine feed and the effects on reproductive health
… characterize the stress relaxation behavior of vaginal tissue in the swine model, (2) determine how ZEN consumption effects the elasticity of pelvic support tissue. (3) determine where ZEN and a related metabolite accumulate in the swine reproductive tract, (4) evaluate the prevalence of ZEN and …
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Anisotropy of Passive and Active Rat Vagina under Biaxial Loading
… is associated with mechanical alterations of the vaginal wall. In order to characterize the complex mechanical behavior of the vagina, we performed planar biaxial tests of vaginal specimens in both the passive (relaxed) and active (contracted) states. Specimens were isolated from virgin, female …
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Functional and Morphological Characteristics of Smooth Muscle in the Rat Vagina
… aim toward filling existing knowledge gaps on vaginal tissue morphology and contractile function of the vagina. First, we quantified the large heterogeneous deformations that the vagina experiences during contractions for the first time. For this study, vaginal specimens were subjected to …
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Development and Evaluation Of HIV gp120 Responsive Microbicide Formulation for the Prevention of HIV Sexual Transmission
… there is an urgent need to develop topical (vaginal/rectal) microbicide formulations capable of preventing HIV sexual transmission. The objective of this dissertation is to develop a mannose specific, lectin-based topical microbicide formulation capable of targeting HIV gp120 for the …
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What to Expect when Mice Are Expecting: Pregnancy-Driven Changes in the Reproductive Tract
… the short and long term such as pre-term birth, vaginal tearing, and pelvic organ prolapse. The female reproductive tract undergoes dramatic changes during pregnancy and postpartum recovery, requiring coordinated efforts across the vagina, cervix, and uterus. From an engineering perspective, we …
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Novel Treatment of Anal Fistulas and Endovascular Drug Delivery for Peripheral Arterial Disease
… is discussed. By closing the opening with a tissue-compatible adhesive patch, less bacteria enters the fistula from the anal or rectal cavity, and the internal opening is fully sealed off to facilitate healing. Preliminary results for rectal, anal, and vaginal tissue show that this patch can …