Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Vaginal Microbiota"”.
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Baboon vaginal microbiota: an overlooked aspect of primate physiology
The bacterial population of the vaginal canal is a primate infant’s first exposure to the microbial community inhabiting the outside world. Yet, little is known about this community and the effect it might have on the development and survival of the infant. Humans and Papio baboons share …
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MODE OF BIRTH AND VAGINAL MICROBIOTA IN REPRODUCTIVE-AGE WOMEN
… that women with robust, Lactobacillus-dominated vaginal microbiotas are less likely to develop a range of adverse reproductive health outcomes. The birthing process is thought to be a critical event in the initial seeding, or colonization, of the human microbiome, and the transfer of microbiota …
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Diversity of vaginal microbiota associated with bacterial vaginosis and the impact on pregnancy outcomes in HIV-infected and uninfected women.
The composition of vaginal microbiota in pregnancy is important as it may influence susceptibility to adverse pregnancy outcomes. Dysbiosis of the vaginal microbiota caused by the replacement of protective resident microorganisms such as Lactobacillus spp. by anaerobic bacteria is known as …
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Characterising vaginal Lactobacillus strains from young South African women with persistently optimal vaginal microbiota – Developing the framework for an African vaginal probiotic product development platform for reproductive health
… results in only a brief resolution of the vaginal dysbiosis present in BV and the recurrence rates are high. Probiotics have been explored as a possible adjunctive treatment option, but most commercially available formulations do not contain vaginally-derived strains and there is limited …
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Human Papillomavirus Infections and Human Papillomavirus Associated Diseases in Nigeria: Distribution, Determinants and Control
… In this thesis, I explore the role of the vaginal microbiota, a host factor and the presence of multiple HPV infections, a viral factor in HPV persistence. Considering the limited data on the epidemiology of HPV related diseases in low and middle-countries (LMIC), and the limited success of …
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Effects of hormonal contraceptives on the female genital tract microbiota in South African adolescents
… changes in the female genital tract (FGT) microbiota. We examined the impact of three different HC methods on the adolescent female genital tract microbiota and related cytokine and HIV target cell levels at the cervical mucosa in a randomized, crossover trial. Study design and methods 131 …
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Characterization of the vaginal microbiome in pregnancy
The vaginal microbiome plays an important role in women's reproductive health. Imbalances in this microbiota are associated with bacterial vaginosis, increased susceptibility to sexually transmitted infections, and negative reproductive outcomes. The causes of such variations, however, are poorly …
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The Role of Microbial Diversity in Female Reproductive Health: An Analysis of the Microbiome's Influence on Pregnancy Outcomes in Postparturient Mares
… however, the terms of infection are unclear, as microbiota has been discovered in placental membranes and amniotic fluid of healthy pregnancies. The objective of this study is to challenge the sterile womb hypothesis and investigate the relationship between microbiota and negative pregnancy …
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Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
… compositions of in-host microbial communities (microbiota) play a significant role in host health, and a better understanding of the microbiota's role in a host's transition from health to disease or vice versa could lead to novel medical treatments. One of the first steps toward this …
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Sex as a Biological Variable in Preclinical Animal Studies with an Infectious Disease Exemplar.
… model, the influence of sex hormones on the vaginal ecosystem was characterized in rhesus macaques across the menstrual cycle. Immune profiling revealed stable peripheral populations (CD45, CD4, CD8, CD56, CD123), with a hormone-dependent increase in CD45 expression associated with elevated …
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The oral microbiota of Irish children in health and disease: a longitudinal and cross sectional study
… community. In the last decade, the oral microbiota of children and adults has been studied in detail using continuously developing DNA sequencing methods. In particular focusing on the oral microbiome changes in the presence of diseases such as dental caries, periodontal disease and the …
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Optimization of Enantiopure tetrahydro-β-carbolines as Potent Antimalarials and Exploration of salicylic acid analogs for combating multidrug-resistant Neisseria gonorrhoeae
… compared to AZM, against N. gonorrhoeae over the vaginal microbiota.
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Optimal clustering techniques for metagenomic sequencing data
… to determine the composition of bacterial microbiota of the human body. Clustering algorithms have been used to search for core microbiota types in the vagina, but results have been inconsistent, possibly due to methodological differences. We performed an extensive comparison of six …
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Fermented foods production using isolated Lactobacillaceae species for the improvement of vaginal health: the case of mageu and yoghurt
Bacterial vaginosis (BV) is the most prevalent vaginal dysbiosis affecting women's reproductive health. The condition is characterised by the disruption of a Lactobacillus spp.-dominated microbiota that is associated with positive health outcomes and a shift to a microbial community that consists …