Global ETD Search
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Showing 1 to 4 of 4 for “"Vacuolating cytotoxin A"”.
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Host cellular defense against metabolic alterations induced by Helicobacter pylori vacuolating cytotoxin A
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
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Characterization of vacuolating cytotoxin A of helicobacter pylori in cell binding and cellular activity
The sensitivity or resistance of host cells to bacterial toxins is often dependent on the presence or absence of cell surface toxin receptors required for the binding and subsequent downstream action of the toxin. Our laboratory has identified plasma membrane sphingomyelin (SM) to be important for …
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Helicobacter pylori gene regulation by virulence region located sRNAs
… and some contain a DNA region called the cytotoxin associated gene pathogenicity island (cagPAI) that encodes virulence factors. Gastrointestinal disease associated with H. pylori are more likely to occur in infections with cagPAI positive strains. Helicobacter pylori has few known …
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Modulation of host metabolism by the human gastric pathogen Helicobacter pylori
… by modulating host cellular homeostasis. Vacuolating cytotoxin A (VacA) is a pore-forming exotoxin of H. pylori, that, once secreted, enters the host cells and targets mitochondria. Previous studies revealed that VacA supports H. pylori colonization by altering host energy metabolism, …