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Showing 1 to 1 of 1 for “"Vacuolar protein sorting 34 (Vps34)"”.
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Non-canonical functions of leucyl-tRNA synthetase: Mechanism of cell growth and skeletal myogenesis
… signaling by mTORC1. The class III PI-3-kinase Vps34 mediates amino acid signaling to mTORC1 by regulating lysosomal translocation and activation of the phospholipase PLD1. In collaboration with Dr. Mee-Sup Yoon, I identified leucyl-tRNA synthetase as a leucine sensor for the activation of …