Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 15 of 15 for “"Vaccine effectiveness"”.
-
Zeolites Structure, Influenza Evolution and Vaccine Effectiveness, with Prediction of Emerging Flu Strain Clusters
… viruses and discusses a way to prediction vaccine effectiveness. Influenza A is a serious disease that causes significant morbidity and mortality, and vaccines against the seasonal influenza disease are of variable effectiveness. In chapter 3, I discuss the use of the pepitope method to …
-
Force Health Protection: Applied Epidemiology in the Australian Defence Force
… an ADF training establishment and estimation of vaccine effectiveness using a test-negative design; an evaluation of the ADF notifiable diseases surveillance system; estimating the prevalence of cardiovascular disease risk factors in the ADF population using data from Periodic Health Examinations …
-
Force Health Protection: Applied Epidemiology in the Australian Defence Force
… an ADF training establishment and estimation of vaccine effectiveness using a test-negative design; an evaluation of the ADF notifiable diseases surveillance system; estimating the prevalence of cardiovascular disease risk factors in the ADF population using data from Periodic Health Examinations …
-
Statistical applications in the analysis of vaccine preventable diseases
… and develops statistical methods to studies of vaccine-preventable disease outbreaks in Scotland and aims to aid in the detection and management of outbreaks.For detecting outbreaks, a system was designed for Health Protection Scotland (HPS) to link cases with incomplete genetic typing data to …
-
Super-resolved volumetric optical imaging of virus-infected cells
… mechanism of two live attenuated influenza vaccine (LAIV) viruses characterised by differing vaccine effectiveness. In both cases, the increased resolution in three dimensions delivered details about the infection mechanism of these viruses that were not previously known. Imaging SARS-CoV-2 …
-
Influenza : a study of contemporary medical politics
… is actually unclear. Furthermore, influenza vaccine effectiveness has been vastly overstated, predictive models of pandemic influenza are demonstrably flawed, and officials conflate true influenza with influenza-like illness (ILl), an often overlooked but critical distinction which allows …
-
Predicting the Antigenic Evolution of Influenza Viruses with Application to Vaccination Strategy
… novelty in wild virus populations. Influenza vaccines contain virus antigen which elicit the production of antibodies that protect against antigenically similar strains. After major antigenic evolution in wild viruses, vaccines must be updated to remain effective. I use a simple model to show …
-
Stochastic and Renewal Methods Applied to Epidemic Models
… reduced by combining two factors: the vaccine effectiveness and the vaccination rate. The impact of these factors on the force of infection can transform an endemic steady state into a disease free state. The second chapter analyses the SIS Epidemic dynamics using the Birth-Death Markov …
-
Strategies for Effective Mitigation of Infectious Diseases, with Focus on COVID-19
… interventions based on factors such as initial vaccine coverage, vaccine effectiveness, compliance rates, and disease transmission dynamics. As COVID-19 variants continue to emerge, we highlight the necessity for adaptive screening strategies that account for the existing variants and …
-
Prediction and surveillance of antigenic variation in influenza and SARS-CoV-2 viruses
… As such, the strain contained in the influenza vaccine must be updated prior to each influenza season to match currently circulating viruses, and individuals must be re-vaccinated in order to maintain antibody-mediated protection. Ensuring that the virus strain contained in the vaccine is a …
-
Long-term follow-up of neonates who have been immunized with hepatitis B vaccine
Although the short-term effectiveness of hepatitis B vaccine has been well established, few long-term studies of the effectiveness of this vaccine in neonates who are born to HBsAg positive mothers have been undertaken. It is also not known if supplementary doses of vaccine are required to protect …
-
Statistical approaches to the evaluation of the impact of vaccination programs : a case study exploring rotavirus vaccination in New South Wales
… their assumptions held. The evaluation of the effectiveness of vaccination programs requires the use of rigorous statistical methods to ensure the robustness and validity of findings. Appropriate statistical methods that account for temporal trends are needed to provide a detailed understanding …
-
Descriptive analysis of routine childhood immunisation timelines in the Western Cape, South Africa
… immunisation schedules is critical in ensuring vaccine effectiveness against vaccine preventable diseases (VPDs). Delays in the uptake of routine childhood immunisations lead to an increase in children susceptible to VPDs. Catch-up vaccination campaigns are strategies aimed at minimising the …
-
Investigating Modular Structure and Function in Biology: from Immunology to Cognition
… precision in genetic editing, improving flu vaccine selection and development, understanding music processing in the brain, and quantifying the cognitive health benefits of a therapeutic arts intervention.
-
Childhood varicella vaccination: an evaluation of clinical effectiveness, safety and cost effectiveness in Ireland
… (chickenpox) is a common, highly contagious, vaccine-preventable disease that mainly affects children. Although typically mild, serious complications requiring hospitalisation do occur. Varicella is also associated with significant productivity loss mainly due to absence from paid work for …