Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Vaccine Stability"”.
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Population Structure of Yellow Fever Virus: Influence of Viral Diversity on Vaccine Attenuation
… wild-type from serially passaged and attenuated vaccine strains. Using deep sequencing techniques, a comparison was made between the prototype West African YFV strain Asibi, and a commercial aliquot of the YFV 17D-204 vaccine. In silico methods revealed the vaccine to be of lower diversity than …
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Engineered microneedles for transcutaneous vaccine delivery
… disease, however despite the successes of modem vaccine development, there remain several notable obstacles for the advancement of vaccine-mediated improvements in global healthcare. Many of the current limitations in vaccine availability and administration are the result of obligate needle-based …
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Investigation of Novel Prophylactics Against Human Rotavirus Using Gnotobiotic Pig Models
… each year. There are two live oral attenuated vaccines licensed for use in the United States that are highly effective in high-income countries but much less so in low-and middle-income countries (LMICs). Several factors contributing to decreased efficacy in these areas include chronic …
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Biologically Inspired Engineering for Protein Stabilisation
… with more efficient vaccination coverage. Thermostability of vaccines is one of the major reasons why many children who need vaccines most do not get all the shots they need. Vaccines need to be kept below 8°C throughout manufacturing, delivering and shipping which requires a cold-chain. This …