Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 1385 for “"Vaccine"”.
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Exploring meaning-making among those who are identified by scientists as vaccine-resistant, vaccine-hesitant, or vaccine-sceptical
Vaccines are an indisputable human right and an important tool in the advancement of world health. Over the last few decades, their function in disease prevention and outbreak management has been increasingly important. Immunization is considered an important investment in one's health, and in …
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Cost-effectiveness analysis of MVA85 vaccine: a new TB vaccine candidate
… remains a major public health concern. The BCG vaccine is, currently, the only vaccine against TB and, although it provides some protection against disseminated forms of TB, its effectiveness in preventing primary infection and disease progression to pulmonary TB is highly varied. A number of …
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Compensation for Vaccine Damage
… a major contributor to public health. Although vaccines have many benefits, there are people who claim that they or their infant children have been injured, often permanently and severely, by the powerful biological agents introduced into their bodies by vaccination. The object of this thesis is …
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Attenuated Mumps Virus Vaccine
Made available in DSpace on 2014-12-09T22:04:14Z (GMT). No. of bitstreams: 1 6615238.pdf: 3524035 bytes, checksum: 8996caa4ae7332a82dfd2fc636633592 (MD5) Previous issue date: 1966
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Molecular modeling studies of carbohydrate vaccine antigens: informing the future of vaccine design
… into the intricate world of carbohydrate-based vaccine antigens by employing molecular dynamics simulations to explore the link between their structure, conformation, and immune function. Through a series of four case studies focused on distinct antigen targets, this research aims to predict …
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Candidate Bivalent HCV Vaccine: A Novel Approach To Vaccine Design for Hyper-variable Viruses
… underscores the urgent need for a prophylactic vaccine. Vaccine development has faltered because the extreme genetic diversity of the virus has precluded the induction of broadly protective antibodies (AB) with classical vaccines. Here, I describe a novel approach to vaccine design for …
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Exploring vaccine decision-making to identify and address barriers to vaccine uptake in Ireland
… achievements of the last century. However, vaccine uptake rates worldwide remain sub-optimal. The vaccine decision-making process is complex and multifaceted and multiple barriers to vaccine uptake have already been identified. However, these barriers are highly variable and context …
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Severe Acute Respiratory Syndrome Coronavirus-2 Vaccine Development: A Virus-Like Particle Vaccine Approach
… protein sequence. In this project, we produced a vaccine against SARS-CoV-2 that was composed of three SARS-CoV-2 Spike protein epitopes inserted into the ∆HBcAg VLP. These insertions included Spike epitopes predicted to induce a humoral and/or cell-mediated immune response. The immunogenicity of …
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Malaria immunology and vaccine development
… latest attempts to produce an effective malaria vaccine. It goes on<br/>to describe the rationale behind the vaccines developed by the University of<br/>Oxford and others. A brief introduction to the process of planning and carrying out<br/>clinical trials of vaccines is then provided, and is …
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Polymer microspheres for vaccine delivery
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1996.
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Vaccine policy & vaccine politics: an analysis of United States vaccine uptake by state-level school and childcare vaccination mandate policies and state-level election results
… costs. Despite overwhelming evidence supporting vaccine safety and effectiveness, skepticism and hostility toward childhood vaccination has grown in recent decades, and has recently become a partisan political issue in the US. Statewide vaccination mandates in schools and childcare centers have …
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DENVax live attenuated chimeric dengue vaccine
… a headache and fever to even death. There is no vaccine to prevent infection by dengue viruses and the only current protection and prevention is mosquito control. The dengue viruses and the Aedes aegypti mosquito that carries them are spreading to more areas of the world and are therefore posing …
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Biopolymer-Hybrid Nanomaterials for Vaccine Formulation
During the last three decades, genetic vaccines have emerged as promising therapeutic strategy to tackle cancers, autoimmune and allergic diseases as well as viral infections. Until recently, the clinical breakthrough of the technique was significantly constrained by stability issues of the …
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Engineered microneedles for transcutaneous vaccine delivery
… disease, however despite the successes of modem vaccine development, there remain several notable obstacles for the advancement of vaccine-mediated improvements in global healthcare. Many of the current limitations in vaccine availability and administration are the result of obligate needle-based …
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Optimization of influenza vaccine strain selection
… (WHO) is responsible for making annual vaccine strains recommendation to countries around the globe. However, various studies have found that the WHO vaccine selection strategy has not been effective in some years. This motivates the search for a better strategy for choosing vaccine …
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Data-driven strategies for vaccine design
… with the same pathogen. Until recently, vaccine development has largely followed empirical paradigms that have proven successful against many diseases. However, many pathogens have now evolved that defy success using the traditional approaches. Rational design of vaccines against such …
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Assessment of three key vaccine attitudes and exploration of their impact on vaccine uptake status in college students.
… in the literature that can be adjusted across vaccine types. Therefore, there is a need for a scale assessing college student personal attitudes and attitudes perceived in parents and friends toward vaccines. Furthermore, there is a need to test and build on mediation models predicting …
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Intradermal Administration of RiVax, a Ricin Vaccine
… RiVax by evaluating the following parameters of vaccine efficacy: (1) short-term antibody responses and protection of mice from a 10X LD50of ricin following a three dose vaccine regimen; (2) long-term antibody responses and protection of mice from a 10X LD50of ricin following a three dose vaccine …
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