Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"VSCC"”.
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The role of Ca²⁺ and cAMP in GnRH-stimulated LH release
… both ROCC and voltage-sensitive Ca²⁺ channels (VSCC). VSCC are not involved in the spike phase of GnRH-stimulated LH release since D600 and nifedipine, inhibitors of VSCC, have no effect on the spike phase. The plateau phase of release is dependent on Ca²⁺ entry via VSCC (about 50%) and ROCC …
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Proteomics characterization of HPV-independent Vulvar Cancer Tumour Progression and Metastasis by Mass Spectrometry
… (dVIN), vulvar squamous cell carcinoma (VSCC) and metastatic lymph nodes (LN). These proteins could be used as tissue markers to distinguish VSCC from dVIN and other vulvar tissues. The following results of this thesis focused on proteins with potential discriminative abilities between …
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Embryonic Epithelial Development is Modulated by Extracellular Calcium
… The voltage sensitive Ca2+-channel (VSCC) antagonists verapamil and nifedipine were used to selectively block Ca2+ influx into the cultured tissue. Both verapamil, a non-specific channel blocker, and nifedipine, which is highly selective for L-type VSCCs, significantly inhibited …
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The Characterization Of Pb2+ Toxicity In Rat Neural Development: An Assessment Of Pb2+ Effects On The Gaba Shift In Neural Networks And Implications For Learning And Memory Disruption
… Pb2+ at low micro molar concentrations induced VSCC-â3 nuclear translocation and GABAAR upregulation. KCC2 expression was inhibiting in cultures by Pb2+. Synaptosomal effects of Pb2+ revealed altered glutamate accumulation and handling with increased spontaneous and decreased evoked release in …
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Vascular Kv7 (KCNQ) Potassium Channels As Therapeutic Targets in Cerebral Vasospasm
… (Ca2+) through voltage-sensitive Ca2+ channels (VSCC) resulting in hyperconstriction (spasm). The spasm of the arteries restricts blood flow to the brain, inducing ischemic neurological deficits and consequential high morbidity and mortality. The cellular pathogenesis of cerebral vasospasm is …