Global ETD Search
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Showing 1 to 7 of 7 for “"VR1"”.
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A Study of Imaging Techniques of 3-Dimennsional CT Diagnosis for Rib Fractures
… of volume rendering images were reconstructed. VR1 was reconstructed from the axial images of 2mm slice thickness and 1mm increment interval. VR2 was from the axial images of 1mm slice thickness and 1mm increment interval and VR3 from 1mm slice thickness and 0.5mm increment interval. VR1` was …
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Charakterisierung von Spinalganglienneuronen intakter und lädierter Afferenzen
… Zytokinen (TNF-α, IL-10), Vanilloidrezeptor 1 (VR1) und Neuropeptiden in Spinalganglienneuronen immunhistochemisch analy-siert. Durch retrograde Anfärbung mit den Tracern Fluorogold (FG) und Fluoruby (FR) konnten intakte von geschädigten Neuronen unterschieden und Muskel- und Hautaffe-renzen …
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Regulation der Capsaicin-Sensitivität von murinen Spinalganglienzellen durch neurotrophe Faktoren
… Capsaicin-Empfindlichkeit, CGRP-Expression und VR1-Expression reguliert. Dieser Rezeptor hat dabei keine Bedeutung für den konstitutiven Cobalt-Uptake, jedoch für die Aufrechterhaltung des Cobalt-Uptakes in der Zellkultur. Zum anderen konnte gezeigt werden, dass GDNF dosisabhängig den Anteil der …
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TRPV1 ist ein polymodaler Rezeptor von nozizeptiven Spinalganglienzellen
… von Wildtyp Mäusen verglichen. TRPV1 (früher VR1; vanilloid receptor 1) wird nahezu selektiv in sensiblen Neuronen exprimiert und wird im heterologen Expressionssystem durch Vanilloide, Hitze (> 43°C) und Protonen aktiviert. Durch diese Eigenschaften scheint TRPV1 für die rezeptiven …
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Functional DNA Aptamers as Biotherapeutic Molecules
… successfully identified a 25-base aptamer (VR11) that can bind with high affinity and specificity to TNFα. VR11 blocked TNFα signaling, prevented apoptosis, reduced nitric oxide (NO) production in cultured cells and was non-immunogenic when injected into C57BL/6 mice. As well, aptamers were …
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A molecular epidemiological analysis of meningococcal isolates within Scotland 1972-1998
… VR types. There was strong evidence of certain VR1, 2 and 3 regions being associated with certain serogroups, although this was not definitive. For example, of 192 isolates with PorA type 19, 15, 36, 85.4% were associated with serogroup B. Genosubtyping of the porA gene has been shown to …
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Studies on transient receptor potential vanilloid subtype 1 (TRPV1)-mediated degeneration of mesencephalic cellsin vivo and in vitro
… vanilloid subtype 1 (TRPV1, also known as VR1) has an oligomeric structure formed by subunits having six transmembrane segments with a pore domain formed by the fifth and sixth transmembrane regions. This receptor is a nonselective cation channel activated by the vanilloids or products of …