Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"VPC fate patterning"”.
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Temporal control of vulval precursor cell fate patterning in Caenorhabditis elegans
… developmental decisions in response to different patterning signals. In this thesis, I present my studies on the temporal control of Vulval Precursor Cell (VPC) fate patterning through analyses of VPC development defects in heterochronic mutants. I show that loss of the miRNA lin-4 inhibits …
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Regulation of the Ras Signaling Network in C. Elegans Development
… equipotent C. elegans vulval precursor cells (VPCs) to assume the 3˚-3˚-2˚-1˚-2˚-3˚ pattern of cell fates. EGF triggers the LET-60/Ras-LIN-45/Raf-MEK-2/MEK-MPK-1/ERK canonical MAP kinase cascade to induce 1˚ fate and synthesize of DSL ligands for the lateral Notch signal. In turn, LIN-12/Notch …