Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"VMP1"”.
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Investigating the role of miR-21 in autophagy and VMP1
… methylated region (DMR) around the miR-21/VMP1 locus in IBD patients compared to HC and elevated levels of VMP1 and miR-21 have been detected in patients. MiR-21 is a microRNA that is associated with immune related disorders, and VMP1 Is a key regulator of autophagy, a pathway heavily …
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Development and application of a high throughput cell based assay to identify apoptosis inducing proteins, and functional characterization of the candidate Vacuole Membrane Protein 1 (Vmp1)
… of the candidates, Vacuole Membrane Protein 1 (Vmp1), which forms vacuoles in cells and subsequently induces apoptosis when overexpressed, has been functionally characterized in detail. It has been reported that VMP1 mRNA is differentially expressed in cancer, acute pancreatitis and kidney …
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Characterization of a Chlamydomonas protein involved in cell division and autophagy
… observe the effect on the CV. One of our genes, VMP1, caused striking, severe phenotypes when silenced. Cells exhibited defective cytokinesis and aberrant morphologies. The CV, incidentally, remained unscathed. In addition, mutant cells showed some evidence of disrupted autophagy. Several …
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The study of two transmembrane autophagy proteins and the autophagy receptor, p62
… include two transmembrane proteins, ATG9 and VMP1. While ATG9 and VMP1 has been discovered for about a decade and half, the trafficking and function of these proteins remain relatively unclear. My work in this thesis identifies and characterises a novel trafficking route for ATG9 and VMP1 and …