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Showing 1 to 11 of 11 for “"VMAT2"”.
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Assoziationsstudien von Kandidatengenen (VMAT2, DAT, BDNF) mit Persönlichkeitsmerkmalen und psychiatrischen Erkrankungen
… Kandidatengene (vesikulärer Monoamintransporter VMAT2, Dopamintransporter DAT, Brain Derived Neurotrophic Factor BDNF) bei Persönlichkeitsmerkmalen und psychiatrischen Erkrankungen näher zu beleuchten. C. Robert Cloninger postuliert in seiner biosozialen Persönlichkeitstheorie eine genetische …
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The Role Of Sertonin And Vesicular Monoamine Transporters In The Adverse Responses To Methylenedioxymethamphetamine
… and the vesicular monoamine transporter 2 (VMAT2) to the physiological, behavioral and neurotoxic responses to MDMA. SERT functions as a primary regulator of 5-HT homeostasis, mediating the reuptake of 5-HT from the synaptic space following its release during neurotransmission. SERT is a …
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Platelet Dense Granules Mature Within Late Stages Of Megakaryocyte Differentiation By Cargo Delivery
… protein vesicular monoamine transporter 2 (VMAT2) and its localization throughout MK differentiation. VMAT2 has been implicated as the transporter responsible for serotonin uptake into DGs and is therefore a likely candidate for a DG protein. Within MKs, VMAT2 localizes to acidic …
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THE EFFCT OF LOW-LEVEL LEAD ON SEROTONIN EXPRESSION IN THE DEVELOPING MOUSE SUPERIOR OLIVARY COMPLEX AND SOMATOSENSORY CORTEX
… the immunoreactivity of serotonin (5-HT) and VMAT2 in the lateral superior olive (LSO). During early developmental, "non-serotonergic" sensory neurons, including LSO neurons and thalamocortical neurons of the somatosensory system, transiently take up 5-HT from the extracellular environment …
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THE EFFCT OF LOW-LEVEL LEAD ON SEROTONIN EXPRESSION IN THE DEVELOPING MOUSE SUPERIOR OLIVARY COMPLEX AND SOMATOSENSORY CORTEX
… the immunoreactivity of serotonin (5-HT) and VMAT2 in the lateral superior olive (LSO). During early developmental, "non-serotonergic" sensory neurons, including LSO neurons and thalamocortical neurons of the somatosensory system, transiently take up 5-HT from the extracellular environment …
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CHRONIC LOW-LEVEL LEAD EXPOSURE AFFECTS THE MONOAMINERGIC SYSTEM IN THE MOUSE SUPERIOR OLIVARY COMPLEX
… for the vesicular monoamine transporter 2 (VMAT2), serotonin, and dopamine beta hydroxylase (DβH, a marker for norepinephrine) in order to elucidate the effect of Pb on monoaminergic input into the SOC. In addition, sections were immunolabeled with antibodies to VGLUT1, VGAT and VAChT in …
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CHRONIC LOW-LEVEL LEAD EXPOSURE AFFECTS THE MONOAMINERGIC SYSTEM IN THE MOUSE SUPERIOR OLIVARY COMPLEX
… for the vesicular monoamine transporter 2 (VMAT2), serotonin, and dopamine beta hydroxylase (DβH, a marker for norepinephrine) in order to elucidate the effect of Pb on monoaminergic input into the SOC. In addition, sections were immunolabeled with antibodies to VGLUT1, VGAT and VAChT in …
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Molecular and Neurochemical Effects of Methylphenidate on the Developing Brain
… of the: vesicular monoamine transporter (VMAT2), dopamine D1 receptor, and the catecholamine rate-limiting enzyme tyrosine hydroxylase (TH), in most of the examined brain areas. By using proton nuclear magnetic resonance (1H-NMR) spectroscopy, this thesis also shows that acute MPH enhances …
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Neuropharmacological Properties of the Histaminergic System in the Zebrafish
… of the vesicular monoamine transporter 2 (VMAT2) was shown to result in an almost total loss of histamine immunoreactivity in neuronal fibres and a decreased number of histamine neurons. Additionally, levels of histamine and other amine neurotransmitters were decreased. Depletion of …
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Characterization of Vesicular Monoamine Transporter 2 and Its Role In Parkinson'S Disease Pathogenesis Using Drosophila
… activities in content release. In particular, VMAT2 orthologue potentially poses a unique, previously unexplored activity in promoting DA release. On the other hand, by examining DA distribution in wildtype and <em>VMAT</em> mutant animals, we find that there exists intrinsic difference in the …
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I. Advanced Fluorescent False Neurotransmitters for the Study of Monoamine Transporter Activity and Synaptic Transmission
… for the Vesicular Monoamine Transporter 2 (VMAT2) for applications in high throughput screening of VMAT activity and inhibition, as well as for imaging aminergic synaptic transmission in brain tissue. Chapter 3 describes the discovery of fluorescent probes FFN201 and AGH093 as dual …