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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 73 for “"VLDL"”.
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Differential Expression Of Proteins Involved In VLDL Trafficking Causes Reduced VLDL Secretion In Male Ames Dwarf Mice
… called very-low-density-lipoprotein (VLDL). VLDLs are crucial lipoproteins responsible for transportation of triacylglycerides (TAGs), chemically inert particles that are physiologically significant for their energy storing capacity, from the liver to peripheral tissues. These VLDL …
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In-vivo Metabolismus der VLDL-Apolipoproteine ApoB, ApoCIII und ApoE
… Untersuchungen beschreiben den Stoffwechsel der VLDLApolipoproteine ApoB, ApoCIII und ApoE bei 6 normolipämischen und einem hypertriglyceridämischen Probanden mit einer endogenen nicht-radioaktiven Tracermethode. Als Tracer wurde mit D3 markiertes Leucin eingesetzt. Nach Abtrennung der …
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A novel pathway for VLDL assembly in the mouse liver
… endosome", transportiert, um lipidiert und als VLDL, in geringerem Umfang auch als IDL, sezerniert zu werden. Diese Daten beweisen, dass als LDL endozytiertes apoB100 zur Synthese von VLDL wiederverwendet werden kann. Eine solche Wiederverwendung von apoB100 wurde bisher nicht gezeigt und stellt …
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IMPACT OF HEPATIC APOLIPOPROTEIN A-IV EXPRESSION ON VLDL PARTICLE EXPANSION, TRIGLYCERIDE SECRETION, AND STEATOSIS
… impact triglyceride (TG) transport by modulating VLDL assembly and secretion. Here we explore the impact of apoA-IV on VLDL particle expansion. Previous studies demonstrated that apoA-IV expression promotes apoB lipoprotein-mediated TG secretion in transfected enterocytes and hepatoma cells. We …
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Estrogen replacement in ovariectomized rats fed safflower oil, coconut oil or cocoa butter: the effects on blood lipids and lipoproteins
… composition of very low density lipoproteins (VLDL) isolated by gel filtration chromatography revealed high levels of cholesterol and protein when rats were fed cocoa butter, and the elevation of cholesterol and protein was especially prominent in VLDL of intact rats. A concomitant rise in VLDL …
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Novel Roles of GLP-1 and GLP-2 in the Regulation of Hepatic Lipid/Lipoprotein Homeostasis and the Involvement of BAT Activation
… in hepatic very low density lipoprotein (VLDL) production. Recent studies have implicated neuronal signalling in the control of hepatic lipid metabolism and VLDL production. The gut derived hormones glucagon-like peptide (GLP)-1 and GLP-2 have been shown to signal through neuronal pathways …
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The effect of feeding either egg white, soy and nonfat dairy protein in male subjects on plasma levels of triglycerides and very low density lipoproteins under controlled conditions
… true for both variables: serum triglycerides and VLDL-triglycerides. Serum triglyceride concentrations for all treatment groups combined at baseline were 79 mg/ 100 ml, increasing to 82 mg/100 ml at week 1 and decreasing to 64 mg/100 ml at week two. An increase of 84 mg/100 ml was noted at week …
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Blood glucose and plasma lipids of Zucker fatty and lean rats fed diets containing cornstarch and sucrose
… and cholesterol concentration. Plasma VLDL were isolated by ultracentrifugation and were assayed for triglyceride. Pooled VLDL samples from each group were separated by size using a 2% agarose column. Sprague-Dawley rats fed sucrose had higher final body weights than rats of the same …
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Polyacrylamide gradient gel electrophoresis for the diagnosis of dysbetalipoproteinaemia (Type III hyperlipidaemia)
… quantitative analysis of centrifugally isolated VLDL. Analysis of VLDL chemical composition is not widely available due to the expense of acquiring ultracentrifuges and the highly-skilled staff necessary to perform the analyses. Genotypic diagnosis is somewhat more widely available, especially …
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INVESTIGATION OF THE CARDIOPROTECTIVE AND HYPOTRIGLYCERIDEMIC POTENTIAL OF ECHIUM OIL AS A BOTANICAL SOURCE OF LONG CHAIN N-3 FATTY ACIDS
… Furthermore, very low density lipoprotein (VLDL) from EO-fed mice incubated with purified lipoprotein lipase (LPL) is significantly more susceptible to hydrolysis than PO-VLDL, and VLDL compositional analysis suggests that EO-VLDL is smaller than PO-VLDL. These results suggest that EO and FO …
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The effects of fish oil versus corn oil on subjects with hyperlipidemia and type II, noninsulin dependent diabetes mellitus
… lowered plasma very low density lipoprotein (VLDL)-cholesterol (p<0.007), plasma triglycerides (TG) (p<0.015), and plasma VLDL-TG (p<0.02) were found in subjects consuming fish oil supplements than in those consuming corn oil. In addition, total plasma TG was decreased by 22 percent (p<0.05) …
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The Relationship between Meat Consumption and the Biological Determinants of Cardiovascular Disease Risk
… lipoprotein (LDL), very low density lipoprotein (VLDL), platelet factor four (PF4), and beta-thromboglobulin (BTG). In addition, the blood pressure (BP) was determined.</p> <p>The systolic (p<0.001) and diastolic BP (p=0.016) were lower in the vegetarian subjects than in the omnivores. The serum …
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Identification of Host Factors Required for Hepatitis C Virus Infection
… in the assembly of very low-density lipoprotein (VLDL) were enriched in membrane vesicles. It was demonstrated that agents inhibiting VLDL assembly also inhibit the secretion of HCV. These studies raise the possibility for treating HCV infection with agents blocking VLDL secretion. HCV infection …
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Hepatic gene networks due to the trans-10, cis-12-conjugated linoleic acid supplementation in growing male mice
… Gpam and Scd), lipid droplet formation (Plin2), VLDL assembling/secretion (Mttp and Cideb), ketogenesis and utilization (Hmgcs2 and Bdh1), fatty acid oxidation (Acox1), glyceroneogenesis (Pck1 and Pdk4). The results suggest that the increased liver weight in response to trans-10, cis-12-CLA may …
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Plasma lipids and lipoproteins in male subjects under controlled conditions of high cholesterol feeding
… cholesterol, triglycerides, and HDL, LDL, and VLDL cholesterol levels were measured at the beginning, weekly throughout the experimental period, and 1 week after completion of the study. No significant changes in any of the measured parameters were observed as a result of the high cholesterol …
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Apoliprotein B metabolism in hamster livers, studied in vitro
… secreted proteins in each system. The rates of VLDL synthesis were increased in cells and slices prepared from animals previously fed sucrose- or fat-rich diets, but the secretion of VLDL was inhibited when diets contained unsaturated fat. The overall synthesis of apolipoprotein B was enhanced …
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Dietary long-chain polyunsaturated fatty acids affect plasma and tissue lipids in chickens
… density lipoprotein + low density lipoprotein (VLDL + LDL) triacylglycerol concentrations which were lower than those for chickens fed CF. Tissue lipids from chickens fed LO contained more 20:5n3 compared with those fed SBO or CF. The amounts of 20:5n3 in tissues from chickens fed LO approached …
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Níveis de lipoproteínas e apolipoproteínas em uma amostra de indivíduos descendentes de Japoneses da região de Cascavel (PR)
… total, HDL-colesterol, LDL-colesterol, VLDL-colesterol, apolipoproteína A-I e B e o padrão eletroforético de lipoproteínas em 96 indivíduos japoneses entre 10 a 89 anos. Para os níveis de triglicerídios, 18,7% dos indivíduos descendentes de japoneses obtiveram valores acima de 200 …
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Metabolite Profiling: Correlates and Associations with Incident Cardiovascular Outcomes
… pattern for very-low-density lipoprotein (VLDL) and CHD, the smallest-sized VLDL particle (VLDL-P) subclass, which comprised the largest proportion of cholesterol content, was strongly associated with higher risks of cardiovascular events independent of HDL, VLDL, LDL, or triglycerides. …
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