Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 18 of 18 for “"VESICLE SIZE"”.
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Non-ionic surfactant vesicles as an Amphotericin B inhaled delivery system for the treatment of leishmaniasis
… In this study, inhaled AmB non-ionic surfactant vesicles (AmB-NIV) were assessed as an alternative AmB formulation, which should reduce costs, enhance drug bioavailability and stability and allow a non-invasive route of administration. AmB-NIV formulations (freshly prepared or lyophilised and …
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Syn-eruptive degassing of a single submarine lava flow : constraints on MORB CO2 variability, vesiculation, and eruption dynamics
… concentrations (mainly of CO2 and H2O) and vesicle size distributions (VSDs) for a unique suite of MORB glasses collected at the East Pacific Rise, ~9° 50′ N. These MORB glasses were collected at ~200 m intervals along an across-axis track over a single flow pathway within the recently …
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Syn-eruptive degassing of a single submarine lava flow : constraints on MORB CO₂ variability, vesiculation, and eruption dynamics
… concentrations (mainly of CO 2 and H20) and vesicle size distributions (VSDs) for a unique suite of MORB glasses collected at the East Pacific Rise, ~9° 50' N. These MORB glasses were collected at -200 m intervals along an across-axis track over a single flow pathway within the recently …
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Interactions of functionalized vesicles in the presence of Europium (III) Chloride
… units into large (LUV's) and giant unilamellar vesicles (GUV's). Electrolyte solutions containing di- and trivalent ions were used to induce inter-membrane interactions. Measurements performed with isothermal titration calorimetry (ITC) revealed that interaction between EuCl3 and ß-diketone …
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High Frequency Irreversible Electroporation (H-FIRE) as a Therapeutic Modality for Liver Cancer Treatment and Its Effect on the systemic Extracellular Vesicle Population
… H-FIRE may impact the release of extracellular vesicles (EVs). This study aims to explore how H-FIRE affects peripheral extracellular vesicle (EV) dynamics, potentially providing insights into its broader systemic effects and implications for biomarker development in canine liver cancer …
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Dynamics of ash eruptions at Vesuvius
… groundmass texture (in terms of Crystal and Vesicle Size Distributions) and glass composition. Volcanic ash holds information about magma dynamics within the volcanic conduit, where fragmentation occurs and eruption style is decided. Results of our investigations have been interpreted in …
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Development and Evaluation of Paclitaxel-Loaded Liposomal Formulations for Targeted Drug Delivery to Breast Cancer
… liposomes were lyophilized. The leakage and vesicle size increase during lyophilization was minimized by using lyoprotectant sucrose in the formulation. Feasibility of developing gas-filled liposomes for ultrasound mediated drug delivery was evaluated using freeze drying gas entrapment method …
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Effects of benzo[a]pyrene and CYP19a1b knockdown on zebrafish development
… feedback loop. We hypothesized that BaP would negatively impact cyp19a1b expression in zebrafish, in turn, adversely affecting development and physiology. Here, we consider whether the toxicities observed following BaP exposure are comparable to those following a transient …
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The effect of hyperosmolarity on fluid-phase and receptor-mediated endocytosis in P388D1 macrophages
… of receptor-ligand complexes into coated vesicles of about 0.1 μm in diameter. The average diameter of primary pinocytic vesicles has been calculated to be 0.24 - 0.28 μm. The discrepancy in size between coated vesicles and the average pinosome diameter can be explained if, in addition to …
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Nanoemulsion-like Polymersomes for Nanoreactors
… and cost. Phase transfer of IL-filled polymer vesicles (polymersomes) from the IL phase to water produces a very stable kind of "nanoemulsion"�. Nanoemulsion-like polymersomes have great potential as they confine a catalyst within the interiors, thus mitigating the mass transfer limitations of …
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Statistical Mechanics of Two-Dimensional Materials; From Biological Membranes to Graphene
… membrane. (ii) Thermal fluctuations of vesicles and nonlinear curvature elasticity---Implications for sized-dependent renormalized bending rigidity and vesicle size distribution: In this work, we discuss the statistical mechanics of closed membranes (vesicles) incorporating both …
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Investigation of stability, dynamics and scope of application of mycobacterial porin MspA: a highly versatile biomolecular resource
… scattering and X-ray crystallography. Nanoscopic vesicle formation of MspA molecules in aqueous media has been thoughroughly investigated. Temperature dependent dynamic light scattering experiments reveal that size of such vesicles is dependent on temperature but is independent of ionic strength …
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Electro-deformation of a moving boundary: a drop interface and a lipid bilayer membrane
… on the deformation of a viscous drop and a vesicle immersed in a (leaky) dielectric fluid under an electric field. A number of mathematical tools, both analytical and numerical, are developed for these investigations. The dissertation is divided into three parts. First, a large-deformation …
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NANOFORMULATION OF BUDDLEJA DAVIDII EXTRACT: DEVELOPMENT AND CHARACTERIZATION OF LIPOSOMES AND NANOFIBERS FOR WOUND HEALING APPLICATION
… as drug delivery systems. This part emphasizes the importance of materials and structures in stabilizing sensitive bioactive molecules and drugs, extending their retention at the wound site, and controlling their release profiles. It serves as the background for the use of botanical …
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Helium isotope geochemistry of oceanic volcanic rocks : implications for mantle heterogeneity and degassing
… fraction of the helium resides within vesicles. Measured concentrations are therefore a function of original helium content, magmatic history, vesicle size and quantity, and grain size analyzed. The helium solubility inferred from the results is 3.7 x 10-4 cc STP/g-atm), which is …
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Anomalous diffusion in anisotropic media
… of spherically bent lamellae in multilamellar vesicles. In the third system, a swollen PDMS network, obstructed diffusion was investigated in the fractal topology. <br> <br>Anisotropic Hydrogels: The structure and ordering of macroscopically oriented anisotropic hydrogels was investigated on …
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SPRAY-DRIED BIOADHESIVE FORMULATIONS FOR PULMONARY DELIVERY
… formulations. Cholesterol was added to increase vesicle membrane rigidity. Proliposomes containing salbutamol sulphate (SS) were prepared by incorporating various lipid:carrier (mannitol or LMH; 1:2, 1:4, 1:6, 1:8 and 1:10 w/w). Prochitosomes including SS or beclomethason dipropionate (BDP) were …
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ΛΙΠΟΣΩΜΑΤΑ ΩΣ ΦΟΡΕΙΣ ΤΟΥ ΠΑΡΑΓΟΝΤΑ ΕΝΕΡΓΟΠΟΙΗΣΗΣ ΤΩΝ ΑΙΜΟΠΕΤΑΛΙΩΝ. ΦΥΣΙΚΟΧΗΜΙΚΕΣ ΙΔΙΟΤΗΤΕΣ ΚΑΙ ΔΡΑΣΗ
… RATIOS 1-10%, WAS STUDIED,AS CONCERNING RESICLE SIZE AND STABILITY DURING AGEING OF LIPOSOMAL POPULATIONS FOR TWO WEEKS AT 4 C AND 25 C. THE INTERACTION OF PROTEIN ALBUMIN WITH PAF CONTAINING LIPOSOMES AT 25 C, AS WELL AS, ITS ENCAPSULATION IN THEM, WERE ALSO STUDIED. TWO METHODS WERE USED IN …