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Showing 1 to 20 of 23 for “"VDAC"”.

  1. Analisi elettrofisiologica delle proteine VDAC umane incorporate nei nanodischi e indagine sui residui di cisteina dell'isoforma 3 VDAC nella funzionalità mitocondriale e nel tamponamento dei ROS

    CONTI NIBALI, STEFANOUniversità degli studi di Catania2022

    … come Voltage-Dependent Anion Selective Channels (VDACs), localizzate nella membrana mitocondriale esterna di tutti gli eucarioti. Le proteine VDAC permettono gli scambi di metaboliti e partecipano a numerose vie cellulari grazie all'interazione con specifici enzimi citosolici e fattori apoptotici. …

    catania Repository record

  2. VDAC and SOD1: two major players in mitochondrial metabolism and in ALS

    MAGRI', ANDREAUniversità degli studi di Catania2014

    … proteins, the Voltage-Dependent Anion Channel (VDAC) and the Superoxide Dismutase I (SOD1) and has been especially focused on the relationships between them in physiological or pathological conditions of the cell. VDAC is a pore-forming protein located in the outer mitochondrial membrane, where …

    catania Repository record

  3. Udział kanału VDAC w patogenezie choroby Huntingtona w oparciu o badania modeli komórkowych

    Grobys, Daria2017

    amu-pl

  4. Magic angle spinning NMR applied to membrane protein 2D crystals : the structure and function of VDAC

    Eddy, Matthew T. (Matthew Thomas)Massachusetts Institute of Technology2012

    … of the 32 kDa human integral membrane protein VDAC, the Voltage Dependent Anion Channel. Our results on VDAC have relied on a number of improvements in NMR methodology described in this thesis. These new methods include '3C-' 3C and 5N- 3C recoupling experiments optimized for measuring …

    mit Repository record

  5. NMR structural and functional studies of the mithochondrial outer membrane protein VDAC by Thomas J. Malia.

    Malia, Thomas J., 1977-Massachusetts Institute of Technology2006

    … has been found previously to interact with VDAC, an outer mitochondrial membrane protein responsible for metabolite trafficking. Here, the NMR-based investigation of VDAC and its interaction with Bcl-xL in detergent micelles is described. As an integral membrane protein VDAC presented a …

    mit Repository record

  6. Chronic low-level Pb exposure during development alters proteins involved in energy metabolism in auditory neurons of the brainstem

    Prins, John

    … activity. The voltage dependent ion channel (VDAC) is an ion channel involved in the regulation of mitochondrial physiology and is a critical component in controlling mitochondrial energy production. No studies to date have investigated the effect of Pb on VDAC, therefore the current series of …

    montana Repository record

  7. Chronic low-level Pb exposure during development alters proteins involved in energy metabolism in auditory neurons of the brainstem

    Prins, John

    … activity. The voltage dependent ion channel (VDAC) is an ion channel involved in the regulation of mitochondrial physiology and is a critical component in controlling mitochondrial energy production. No studies to date have investigated the effect of Pb on VDAC, therefore the current series of …

    montana-tech Repository record

  8. Regolazione trascrizionale delle isoforme VDAC umane: analisi dei loro profili di espressione, dell'attività del promotore e dei regolatori trascrizionali

    ZINGHIRINO, FEDERICAUniversità degli studi di Catania2021

    I VDAC (Voltage Dependent Anion-selective Channels) sono proteine canale localizzate nella membrana mitocondriale esterna dove mediano principalmente gli scambi metabolici tra citosol e mitocondri. Negli eucarioti superiori, i VDAC formano una famiglia multigenica che include tre isoforme (VDAC1-3) …

    catania Repository record

  9. Microtubule Regulation of Mitochondrial Bioenergetics in Cardiac and Skeletal Muscles

    Ramos, Sofhia Verena2020

    … into the voltage gated dependent anion channel (VDAC) embedded in planar lipid membranes which was speculated to prevent ADP/ATP cycling. Such regulation could be profound given ADP/ATP cycling kinetics determine the rate of oxidative phosphorylation and reactive oxygen species (ROS) emission key …

    york Repository record

  10. VDAC1P8 as a Novel Regulatory Element in Leukemogenesis: Integrative Genomic, Epigenetic, and Functional Insights [VDAC1P8 come nuovo elemento regolatorio nella leucemogenesi: approfondimenti genomici, epigenetici e funzionali integrati]

    LUCIANO, DANIELAUniversità degli studi di Catania2025

    … come Voltage-Dependent Anion Selective Channels (VDAC), localizzate nella membrana mitocondriale esterna di tutti gli eucarioti. Le proteine VDAC consentono lo scambio di metaboliti e partecipano a numerosi processi cellulari grazie alla loro interazione con specifici enzimi citosolici e fattori …

    catania Repository record

  11. Untersuchung sub-mitochondrialer Proteinverteilungen in unbehandelten und apoptotischen humanen Zellen mittels STED-Mikroskopie

    Neumann, Daniel2012

    … Der voltage-dependent anion-selective channel (VDAC) ist ein Protein der äußeren mitochondrialen Membran, welches für den Transport von Metaboliten wie ATP verantwortlich ist. Im Menschen sind drei verschiedene Isoformen beschrieben. Bis jetzt ist wenig über Unterschiede zwischen den einzelnen …

    goettingen Repository record

  12. Structural characterization of the Voltage-Dependent Selective Anion Channels (VDACs)

    PITTALA', MARIA GAETANA GIOVANNAUniversità degli studi di Catania2020

    … Selective Anion Channel Isoforms (VDACs), the most abundant proteins of the Outer Mitochondrial Membrane (OMM) where they form aqueous pores which allow the passage of ions and small molecules. VDACs are involved in complex interactions regulating organelle and cellular functions …

    catania Repository record

  13. Regulation of BAX/BAK-Dependent Cell Death Program

    Kim, Hyungjin2011

    … c-releasing BAK oligomers but instead includes VDAC/ANT channels that regulate ATP/ADP transport to support ATP production by oxidative phosphorylation. tBID overexpression induces cell death in the absence of Apaf-1 by inhibiting VDAC-mediated ADP import into the mitochondria in a BAK-dependent …

    wustl Repository record

  14. Ankyrin Dependent Mitochondrial Function and Bioenergetics In The Heart

    Subramaniam, Janani, <p>0000-0002-0533-7687</p>2023

    … (Sig1R), and Voltage Dependent Anion Channel (VDAC) at MAMs to constitute a Ca<sup>2+</sup> signaling domain.</p> <p>Through a series of cellular fractionation, co-immunoprecipitation, functional assays, and fluorometry, we evaluated AnkB dependent protein complex formation at MAMs and the …

    uthsc Repository record

  15. Rgs16 is a Pancreatic Reporter of Chronic Hyperglycemia in Diabetes

    Ocal, Ozhan2012

    … postnatal vessel and ductal associated cells (VDAC). Euglycemic adults lacked pancreatic Rgs16::GFP expression. We investigated diabetic mice to determine if Rgs16::GFP would reactivate during beta cell expansion in adulthood. The type 1 diabetic models of beta cell death were streptozotocin …

    utswmed Repository record

  16. Patterning the Mud Snail Ilyanassa obsoleta: The Role of Cell Signaling and Asymmetric Protein Localization

    Gharbiah, Maey MonirThe University of Arizona.2009

    … voltage-dependent anion-selective channel (VDAC) as one of the candidate proteins enriched in polar lobe isolates. I propose that VDAC is asymmetrically distributed by the polar lobe to the D cell and that it may function in D cell induction and mesendoderm fate specification.Lastly, I …

    arizona-thes Repository record

  17. Role and regulation of mitochondrial permeability transition in cell death

    ZHANG DAWEI2008

    … OPA1 and cytochrome c release independently of VDAC and the outer membrane indicating that the MPT is an inner membrane phenomenon. Lastly, the MPT was regulated by the electron transport chain since THG-induced cell death was inhibited in cells lacking mtDNA.

    nus Repository record

  18. Efeitos de dieta hiperlipídica pós-desmame sobre a bioenergética mitocondrial e metabolismo oxidativo de fígado de ratos submetidos à dieta hipoproteica perinatal

    BARROS JÚNIOR, Idelfonso Beltrão deUniversidade Federal de Pernambuco2019

    … entre os grupos. Na análise da expressão de VDAC, houve aumento comparando os grupos NP-HL e NP-NL (16,03%, p <0,05), LP-NL com LP-HL (17,97%, p <0,01), como também entre LP-HL e NP-HL (15,10%, p <0,05). Este estudo mostrou que dieta hiperlipídica enriquecida com AGS induz a disfunção …

    brazil-ufpe Repository record

  19. Content and Activity of Cytochrome P450 3A in Rat Brain Microsomes and Mitochondria

    Alshammari, Nouf

    … the microsomal (calreticulin) and mitochondrial (VDAC) markers. Different concentrations of midazolam were incubated with rat brain microsomes and mitochondria in a side-by-side comparison over a period of 10 minutes.</p> <p>The method was developed and optimized to determine the Michaelis-Menten …

    chapman Repository record

  20. Formazione di proteine canale: dal mitocondrio a SARS-CoV-2. Caratterizzazione funzionale e strutturale attraverso l'uso di tecniche respirometriche e di dinamica molecolare

    CUBISINO, SALVATORE ANTONIO MARIAUniversità degli studi di Catania2023

    … Tra le principali porine riconosciute, vi è VDAC (Voltage Dependent Anion Channel), che tra le sue funzioni ha il trasporto di numerose molecole, tra cui ioni e metaboliti vari, tra cui composti vari coinvolti nei processi neurodegenerativi, come gli aggregati di α-sinucleina, principali …

    catania Repository record

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