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Showing 1 to 2 of 2 for “"UvrABC"”.

  1. Structure/function analyses indicate novel roles for mycobacterial DnaQ homologs in genome maintenance

    … bind either the β-clamp or the components of the UvrABC system. Opposing phenotypes between DnaQ-UvrC (M. tuberculosis Rv2191; M. smegmatis MSMEG_4259) and uvrC deletion imply a DNA-damage specific NER in mycobacteria. This was further confirmed using a combination of gene knockout, site-directed …

    cape-town Repository record for Structure/function analyses indicate novel roles for mycobacterial DnaQ homologs in genome maintenance (opens in a new tab)

  2. Structural and Biochemical Investigation of the Molecular Mechanisms of DNA Response and Repair in Humans and <em>Escherichia coli</em>.

    <p>The genomes of all living cells are under constant attack from both endogenous and exogenous agents that damage DNA. In order to maintain genetic integrity a variety of response pathways have evolved to recognize and eliminate DNA damage. Replication protein A (RPA), the eukaryotic …

    etsu Repository record for Structural and Biochemical Investigation of the Molecular Mechanisms of DNA Response and Repair in Humans and <em>Escherichia coli</em>. (opens in a new tab)