Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Uterine smooth muscle"”.
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Characterization of NADPH Oxidases in Uterine Smooth Muscle during Pregnancy
During gestation, the uterine smooth muscle, or myometrium, transforms from a quiescent tissue to a contractile muscle required for parturition. Immune system activation is a crucial precursor to labour during which the myometrium is infiltrated by immune cells. Immune and myocyte activation rely …
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Observations of idazoxan and xylazine on the myometrial response of the normal, cycling virgin rat in vitro
… the contractile responses of normal virgin rat uterine smooth muscle to the ⍺₂ adrenergic agonist, xylazine HCl, in the presence or absence of the selective ⍺₂ adrenoceptor blocker, idazoxan HCl. Sections of full thickness uterus measuring 5 x 1 x 1 mm taken from mature, virgin Sprague-Dawley …
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Evaluation of bioactivity of a peptide QUB-1669, from the skin secretion of the African running frog, Kassina senegalensis
… anticancer effects, enzyme inhibitor effects, smooth muscle inhibition or relaxation effects, etc., and they are also the current research hotspots of many scientists. <br/><br/>In this experimental study, a new pharmacologically active peptide QUB-1669 was studied. This is a C-terminal …
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Biomechanics of cervical function in pregnancy : case of cervical insufficiency
The uterine cervix is a passive organ in the female body. Its normal function in pregnancy is to stay firm and closed for the duration of the gestation. At term, under the action of coordinated contractions from the myometrium the cervix dilates sufficiently to allow for the delivery of the fetus. …
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Phosphorylation of the Estrogen Receptor Alpha (ERα) at Serine 118 by Phospho-p44/42 MAPK and Regulation by Estrogen and Progesterone in Human Uterine Leiomyoma Tissue and Cells
<p>It is thought that the growth of uterine leiomyomas may be mediated by the interaction of estrogen receptor alpha (ERα) and growth factor pathways and that phosphorylation of ERα at serine 118 (ERα-phospho-Ser118) is important in this interaction. In tissue, immunoblotting and …
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Generation and characterization of spred-2 knockout mice
… high and specific Spred-2 expression in vascular smooth muscle cells and previous studies showed an interaction of Spreds with RhoA, a key regulator of vascular smooth muscle contraction, the regulation of smooth muscle contractility seems to be a good candidate of this phenomenon. Moreover, …
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Role of transient receptor potential channels in mammalian oviduct and uterine epithelia
… and death .It also plays a critical role in uterine smooth muscle contraction and embryo implantation. This thesis is concerned with calcium homeostasis in epithelial tissue lining the oviduct and uterus which are key players in early reproductive events, being involved in gamete transport, …
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Extracellular-matrix mediated regulation of human uterine leiomyoma smooth muscle cells and potential targeting by the anti-fibrotic drug halofuginone
Uterine leiomyomas are known as the most commonly occurring neoplasms in women during their reproductive years. The overall incidence of these benign tumors can be as high as 70-80%, which represents a significant health problem to women. Patients suffer from abnormal uterine bleeding, pelvic pain, …