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Showing 1 to 3 of 3 for “"Uterine NK cells"”.
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The role of uterine natural killer cell-inhibition in pregnancy
Education of natural killer (NK) cells is a genetically determined process that primes NK-cell activity upon the binding of their inhibitory receptors to self-ligands. Although NK-cell education is predictable and measurable in the laboratory, its biological significance is unknown. This thesis …
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Molecular definition of group 1 innate lymphoid cells in the uterus
Uterine NK cells (uNKs) are group 1 (g1) innate lymphoid cells (ILCs) that have been shown to regulate remodelling of uterine blood vessels, an event necessary to support fetal growth. Recently, other ILCs were identified in the mucosa and wall of the uterus of mice and women, pregnant or not. They …
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Immunogenetic regulation of Natural Killer cell function in pregnancy
Uterine NK (uNK) cells are a distinct subset of NK cells in the decidua of humans and rodents during pregnancy, which are essential for remodelling of the spiral arteries supplying the feto-placental unit. Similarly to peripheral NK cells, uNK cells express Natural Killer receptors (NKRs) that …