Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Uropathogenic Escherichia coli"”.
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The Nature of Uropathogenic Escherichia coli ST127
Uropathogenic Escherichia coli ST127 is a recently emerged clone that is reported to cause a small, but significant, proportion of urinary tract infections. Paradoxically, the low prevalence of ST127 in most published studies is also accompanied by a virulence potential significantly higher than …
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A Proteomics Approach to Investigate Uropathogenic Escherichia coli
Uropathogenic Escherichia coli (UPEC) is the most commonly known cause of urinary tract infection (UTI). The possession of many virulence factors and global dissemination of multi-drug resistant UPEC strains is posing a critical risk to treatment worldwide. The most virulent UPEC strains have …
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Intercellular communication in uropathogenic Escherichia coli and the probiotic Lactobacillus reuter
… (AI-2) in the regulation of virulence factors of uropathogenic Escherichia coli J96, determine if the probiotic Lactobacillus reuteri RC-14 produced AI-2, and evaluate if secreted products from the probiotic could affect pathogen recognition by the host. Disruption of luxS (AI-2 synthesis) in E. …
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Pilus biogenesis in uropathogenic Escherichia coli : An electrophysiology study on the PapC usher
Uropathogenic Escherichia coli are the main causal agents of urinary tract infections. Pili are bacterial surface adhesive organelles that are critical virulence factors in the successful colonization of the urinary tract by uropathogenic E. coli. Pili are composite in structure and are formed from …
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Studies on the architecture and on transferability of pathogenicity islands of uropathogenic Escherichia coli strain 536
… and functional analysis of DNA regions of uropathogenic Escherichia coli strain 536 that belong to the flexible E. coli gene pool. The first part of this thesis focused on the identification and structural characterisation of pathogenicity island V of strain 536 (PAI V536). PAI V536 is …
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Studies on the Role of Histone-like Proteins in Gene Regulation in Uropathogenic Escherichia coli Isolate 536
… of histone-like proteins in gene regulation in uropathogenic Escherichia coli isolate 536 was monitored. The histone-like nucleoid structuring protein H-NS is a global regulator in Escherichia coli that has been intensively studied in non-pathogenic strains. No comprehensive study on the role of …
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Investigating the effect of prophylactic D-mannose treatment on adhesion of Uropathogenic Escherichia coli to the human bladder epithelium
… annually, mainly women, and primarily caused by Uropathogenic Escherichia coli (UPEC). Treatment of UTIs is challenged by the continued increase of antibiotic resistance, and alternative strategies are necessary to reduce this disease burden. The pathology of UTI rapidly develops when …
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Identification and characterisation of Group 3 Innate Lymphoid Cells in the renal tract
… The commonest cause of uncomplicated UTI is Uropathogenic Escherichia coli and we used this organism in murine models to interrogate the role of ILC3s within this setting. The project focussed on three vital components of effective defence: the epithelium, mononuclear phagocytes (MNPs) and …
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Characterization of β-lactamases and Porins in Uropathogenic E. coli
Uropathogenic Escherichia coli, the predominant causative agent of urinary tract infections, are becoming increasingly resistant to commonly utilized β-lactam antibiotics leading to higher medical costs, prolonged treatment from persistent infections, and increased mortality. This rising resistance …
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Conservation Of The Intracellular Bacterial Community Pathogenic Pathway In Urinary Tract Infection
… 13 million women annually in the United States. Uropathogenic Escherichia coli: UPEC) is the predominant etiologic agent of UTI; however, several other uropathogens, including Klebsiella pneumoniae, are also significant causative agents. In a murine cystitis model, UPEC utilize a multistep …
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Innate immunity in defence against infection and tissue repair of the urinary tract
… their lifetime. Most infections are caused by uropathogenic *Escherichia coli* (UPEC) and are limited to the lower urinary tract (cystitis), but ascending infection (pyelonephritis) can lead to fibrosis and the development of chronic kidney disease. A complex network of tissue-resident immune …
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Escherichia Coli ST131 Collected From Companion Animals Can Cause Cystitis and Pyelonephritis in a Murine Model of Urinary Tract Infection
Background: Uropathogenic Escherichia coli (UPEC) cause 80% of uncomplicated urinary tract infections (UTI) globally. Since the mid- 2000s, a subset of UPEC called ST131 have undergone rapid pandemic spread. ST131 are a major cause of UTIs that lead to serious complications in humans like …
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Characterization of Virulence Mechanisms in Vibrio parahaemolyticus
Pages xvi-xix are misnumbered as pages vi-ix.