Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Urological malignancies"”.
-
Hypoxia regulated pathways in urological malignancies
Introduction: Kidney Cancer accounts for approximately 2% of all new cancer diagnoses in<br/>the UK each year. Patient survival has improved over the past few decades; however the<br/>mechanisms of this are yet to be fully elucidated. Hypoxia inducible factor isoforms, HIF-1 and<br/>HIF-2, are …
-
Ageing and regeneration-associated transcriptional state transitions and tumour-stroma interaction in early renal carcinogenesis
Kidney cancer is the 14th most common cancers in the world, among which clear cell renal cell carcinoma (ccRCC) is the most common subtype. VHL inactivation is the most common mutation seen in ccRCC with more than 90% of tumours had clonal disruption of the VHL pathway. Although it is the initial …
-
Circulating Tumour DNA in Localised Urological Cancers
… a need for informative biomarkers in localised urological cancers. At present, no method can accurately distinguish between indolent and aggressive prostate cancers, and men often require repeated biopsies. Patients with muscle invasive bladder cancer undergo neo-adjuvant chemotherapy (NAC) to …