Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 74 for “"Urogenital"”.
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Axl RTK and microRNAs in urogenital cancers
This thesis is based on four projects focused on the Axl receptor tyrosine kinase (RTK) and microRNAs in clear cell renal cell carcinoma (ccRCC) and in prostate cancer (PCa). Paper I focuses on differentially expressed microRNAs in ccRCC. We used bioinformatics methods to identify candidate …
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PATHOLOGY OF THE UROGENITAL TRACT IN DOMESTIC ANIMALS
Even though pathology of the urogenital tract in domestic animals is a wide field of research several topics are still poorly investigated, tumors in particular. Moving from this observation, my research is organized into two main topics: canine urothelial carcinoma and tumours of the genital …
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Beta-Catenin and Development of the Urogenital System
The urogenital system is composed of the kidneys, gonads, urinary and reproductive tracts. Components of the urogenital system play many important roles in the body; kidneys function by regulating the body's fluid volume, acidity and mineral composition, while the reproductive tract is necessary …
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Microanatomic structure of cetacean skin in the urogenital region
… may be microanatomic specializations in the urogenital slit and mammary region of cetaceans. There may be an integumentary-linked mechanism in these animals similar to that which causes the milk let-down response in terrestrial mammals. This hypothesis was tested on tissue samples from …
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Regulatory dynamics of the Tbx18 locus in mouse urogenital development
… structures from the prostatic rudiment, the urogenital sinus. Beginning in late gestation, the urogenital sinus begins differentiation under the influence of testicular androgens. Continuing from birth through puberty, the urogenital sinus grows and differentiates into the adult prostate. The …
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Determinants of Upper Genital Tract Complications in a Chlamydial Urogenital Mouse Model
… in a murine model of recurrent chlamydiae urogenital infection. The development of an in vivo model of urogenital Chlamydia trachomatis infection is central to defining the risk of developing long term reproductive complications, delineating potential biomarkers for chlamydial-induced …
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First detection of otarine herpesvirus-1 in South America: Characterizing the epidemiology in a Peruvian pinniped population
… (OtHV-1) is associated with high rates of urogenital carcinoma in free-ranging California sea lions (Zalophus californianus), but rarely considered a conservation concern in the southern hemisphere. The objective of this study was to survey free-ranging South American sea lions (Otaria …
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Passive surveillance of STI pathogens in Cape Town, South Africa: A six-month molecular epidemiology study
… as a surveillance tool in our setting. Methods: Urogenital swabs, submitted to Groote Schuur Hospital over a period of 6 months, for routine microbiological investigations, were subjected to a commercial multiplex PCR assay to determine the distribution of STI pathogens. Correlations between …
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Cell Death as a Morphogenetic Basis for Abnormal Development in Mutant-Bearing and Teratogen-Treated Embryos.
… for the proper formation of the excretory and urogenital duct systems in vertebrates (Saunders, 1966). Cell death also has an important role in the contouring of some organs. The sculpturing of the chick wing is related to precisely timed cell death (Saunders, Gasseling, and Saunders, 1962) as …
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Trends in Chlamydia trachomatis Treatment Prescribing Practices in King County, Washington, 2010 - 2018
… change. We included all female cases of urogenital CT aged >15 years who resided in King County and were diagnosed from 2010-2018. Our dataset contained information on demographic factors, sexual history, clinical features, diagnosing facility, year, and treatment regimen. We conducted …
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Estudo sobre as espécies brasileiras de Astraea Röding, 1798 (Mollusca, Gastropoda, Turbinidae)
… of soft parts, mantle cavity, digestive and urogenital systems, similarities and diferences are regarded and discussed, the respective synonymies are given. The comparative conchology of the Brazilian species with A. (Astralium) phoebia Röding, 1798 and A. (Lithopoma) americana (Gmelin, 1791) …
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Involvement of the WT1 and p16 genes in Wilms' tumour and human malignant mesothelioma
… are known to contribute to development of the urogenital system and the mesothelium (WTI) and to control of the cell cycle (pi6).
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Plasticity of neurons in mouse major pelvic ganglia in response to loos of physiological input in cases of nerve injury and spinal cord injury
… of postganglionic neurons that innervate the urogenital organs and are a part of the neural pathway that controls micturition. In mice, there is one MPG on each side of the animal. MPG receives cholinergic parasympathetic input from the preganglionic neurons in the sacral cord through pelvic …
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Identification of mesenchymal genes involved in prostate organogenesis by LongSAGE analysis
… at puberty. The male and female embryonic urogenital sinus (UGS) both contain a prostate precursor, but due to the action of testosterone only the male will develop a prostate. Testosterone acts in concert with paracrine signalling from inductive mesenchyme to regulate epithelial growth and …
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ΜΕΛΕΤΗ ΤΗΣ ΠΑΡΑΓΩΓΗΣ IGA1 ΠΡΩΤΕΑΣΗΣ ΑΠΟ MYCOPLASMA ΚΑΙ UREAPLASMA ΑΝΘΡΩΠΟΥ ΚΑΙ ΖΩΩΝ
… OF UREAPLASMA UREALYTICUM ISOLATED FROM HUMAN UROGENITAL TISSUES CLEARED HUMAN IGA1, BUT NO CLEAVAGE OF HUMAM IGA2 OR MURINE, PORCINE OR CANINE IGA WAS OBSERVED. UREAPLASMA ISOLATED FROM NONHUMAN HOSTS DID NOT CLEAVE HUMAN IGA1. TWO STRAINS OF CANINE UREAPLASMA WERE ABLE TO CLEAVE CANINE IGA …
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Bedeutung der Miktionsurosonographie in der Diagnostik von Harnwegsinfektionen und bei angeborenen Fehlbildungen der Niere und ableitenden Harnwege im Kindesalter
… urinary tract infections (UTI) and congenital urogenital anomalies. Voiding cystourethrography (VCUG) used to be the gold standard for diagnosing VUR. However, because of the associated radiation exposure, the importance of VCUG has decreased in the clinical practice. Thus, voiding …
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The role of Wt1 in Müllerian duct development
… transcription factor widely expressed in the urogenital system. Human mutations of <em>WT1</em> lead to pediatric nephroblastoma as well as frequent differences of sex development (DSDs). Previous studies have suggested that WT1 acts as an activator for <em>Amhr2</em>, a necessary component of …
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A bioactive peptide from the skin secretion of the Chinese bamboo odorous frog, Odorrana versabilis
… nervous, immune, gastrointestinal, respiratory, urogenital, and dermal systems. Tachykinin peptides are an important neuropeptide family, which have been attracting increased research attention as members may have some clinical effects in some diseases.<br/>
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Regulatory dynamics of transcription factors TBX18 and WT1 in mouse prostate development
… pathology, we compared gene expression in the urogenital sinus (UGS), from which the prostate develops, in Tbx18-null and wild type littermates at two embryonic stages. Genes that regulate cell proliferation, smooth muscle differentiation, prostate epithelium development, and inflammatory …
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Modeling Renal Anomalies Associated with Li-Fraumeni Patients: A Novel Role for p53 in Kidney Development
… these patients have an increased prevalence of urogenital anomalies (36%) as compared with the general population (10%) [1]. Considering individuals with LFS are predisposed to cancer due to mutations in <em>TP53, </em>and they have a higher occurrence of congenital anomalies of the kidney and …
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