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Showing 1 to 3 of 3 for “"Urm1"”.
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A systems biology approach unravels the biological function of two tRNA wobble base modifications in fine-tuning translation and the response to environmental stress
… by the <i>ELP</i>- and <i>URM1</i>-pathways, respectively. Several <i>in vitro</i> experiments have implicated these modifications in modulating wobbling capacity. Moreover, mutations in the <i>ELP</i>- and <i>URM1</i>-pathway genes have been associated with physiological …
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Mechanisms and regulation of dsDNA break repair in the Sulfolobus genus of thermophilic archaea
… modifications. There has been speculation that Urm1 may play a similar role to ubiquitin in the proteasome degradation pathway and we have recently provided evidence to corroborate this. Here the potential for modification of Mre11/Rad50/HerA/NurA by Urm1 was investigated. Indeed Rad50 shows …
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Development and Application of Mass Spectrometry Based Methodologies to Study Ubiquitin-Like Modifiers
… mcm5s2U tRNAs which are co-modified by the UBL URM1, have a much greater impact on protein translation efficiency than the ELP-only modified mcm5U tRNAs.