Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Upstream and downstream processing"”.
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A study of bioprocess designs for development of the myogenic secretome as a source of bioactive extracellular vesicles
… secretome at therapeutically relevant yields. An upstream process for myogenic secreted EVs and proteins was optimised over 7-days. Analytics involved quantification of secretome yield and extracellular vesicle (EV) characterisation. Internalisation of myogenic EVs by human chondrocytes was …
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Development of monoclonal antibody cell culture processes and antibody characterisation
… therapeutics due to their high specificity and efficacy for a wide range of diseases. This research project aimed to establish an end-to-end laboratory-scale monoclonal antibody production process, including upstream cell culture, downstream purification and analytical characterisation. A …