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Showing 1 to 1 of 1 for “"Unstrained dienophile"”.
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Developing unstrained alkenes and alkynes for bioorthogonal chemistry
… decade, challenges lie in finding the suitable dienophiles. Strained dienophiles, for example, trans-cyclooctene derivatives, can undergo ultrafast IEDDA reactions and therefore have been extensively developed. Unstrained alkenes and alkynes, however, have not been well investigated as IEDDA …