Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 92 for “"Unit Operations"”.
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Simulating full-scale drinking water unit operations on pilot-scale
Includes bibliographical references (pages 97-99).
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Polymer fabrication and microfluidic unit operations for medical diagnostics on a rotating disk
Die vorliegende Arbeit ist motiviert durch den in der medizinischen Diagnostik <br>anhaltenden Trend hin zu dezentralen, patientennahen Untersuchungen (Point of <br>Care) und dem Potential der Mikrofluidik, diesen Trend zu unterstützen. Ziel der <br>Arbeit ist die Entwicklung einer zentrifugalen …
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Analysis of the introduction of new technologies to evaluate the performance of pharmaceutical unit operations
Thesis (M.S.)--Massachusetts Institute of Technology, Technology and Policy Program, 1998.
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The Effect of Thermal Processing Schedules and Unit Operations on the Quality of Blue Crab (Callinectes sapidus) Meat
The effects of initial thermal processing, plant sanitation, and employee habits on the microbiological quality of blue crab (Callinectes sapidus) meat were determined in a commercial crab processing facility. Thermal processing was evaluated at 5, 7, and 8 minutes at 250ï °F for the destruction of …
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Application of First Principle Modeling in Combination with Empirical Design of Experiments and Real-Time Data Management for the Automated Control of Pharmaceutical Unit Operations
… products to adjust downstream manufacturing operations (feedforward control). These controls enable increased process understanding, continuous process and product improvement, assurance of product quality, and the possibility of real-time release. Control systems require significant planning …
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A FR 13 microbiological global risk model: demonstrated for pasteurization of raw milk with viable Mycobacterium avium subsp. paratuberculosis
Steady-state unit-operations are used globally in chemical engineering processing. Importantly however, there are naturally occurring (random) fluctuations in parameter values about a ‘set’ mean. These are not sufficient to be considered transient and a random change in one is often off-set by a …
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Artificial intelligence infrastructure into material attributes insights
… sources of variation throughout each of the unit operations in the drive toward six sigma manufacturing. The primary goal of this project is to develop a novel way to assess the variation in raw materials attributes throughout the life-cycle of the material and gain insights about the …
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Globalization of biopharmaceutical manufacturing
… in US and EU perform a larger number of operations within their facilities and also more technically complex operations than facilities in Asia. US facilities support the most complex products (median unit operations =13) and processes (cell culture, purification) and maximum average …
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Modelling material mass balances over wastewater treatment plants
… (ISS) concentrations mass balances models for unit operations in municipal WWTPs. The development of such a model, for both steady state and dynamic simulation conditions, is an objective greater that this thesis project, however, it makes a number of significant steps towards it.
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Water minimisation at Skorpion zinc
… optimisation cannot occure through focus on unit operations in isolation, but rather to use the interactions between the different operations to optimise the process systematically.
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The Production of Low Ash Coals Using the Hydrophobic-Hydrophilic Separation Process with Novel Developments
… work on the interaction between two primary unit operations in the HHS process: oil agglomeration and de-emulsification. Lastly, to make the HHS process more viable for commercial scale-up, a novel unit operation called enhanced liquid flotation (ELF) was developed and tested that performs …
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Process integration in the optimisation of amidase production from recombinant Escherichia coli
… (EBA) was assessed as a tool for minimising the unit operations in the amidase purification train. The EBA process can integrate up to four steps by merging processes involved in centrifugation, microfiltration and initial adsorption into one unit operation.
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Exploring the factors at play to make wastewater biorefineries a reality
… designs. Stoichiometric mass balances of all unit operations are established, showing the material value flows, and combined to model this multi-bioreactor approach. Subsequently the model is tested against literature data. Finally, the applicability of the wastewater biorefinery concept for …
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Investigation into the bioremediation and benefication of olive-derived wastewaters from the Western Cape
… facilities. In addition, the combination of unit operations, such as an extraction system and a biological degradation system, would allow for the recovery of a valuable product that would offset the cost of producing a treated effluent.
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Melt extrusion and continuous manufacturing of pharmaceutical materials
… continuously, reduces the total number of unit operations, allows for incorporation of difficult-to-process drug substances, and has the potential to achieve tablets of better quality and consistency compared to traditional methods. Thus, our goal was to evaluate melt extrusion as a viable …
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Effects of solution complexation on crystallization processes
… enhancing the controllability of crystallization unit operations, providing a new process handle for chemical engineers with which they can create new crystal forms, enhance product purity, improve yields, or inhibit the formation of undesirable crystals. This thesis focuses on the use of …
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A collaborative, multi-agent based methodology for abnormal events management
Modern chemical plants have complicated unit operations with considerable recycles. The complex controls and instrumentation installed often compensate and conceal faults, causing many faults in the process to remain undetected, until serious consequences occur. This thesis strives to explore new …
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Equation-oriented modeling, simulation, and optimization of integrated and intensified process and energy systems
… material and energy balance equations of process unit operations as differential-algebraic equation (DAE) systems that are statically equivalent to the original model. I show that these pseudo-transient models improve the convergence properties of equation-oriented process flowsheet simulations by …
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Multi-scale analysis and simulation of powder blending in pharmaceutical manufacturing
… micro-to-macro approach as a valid way to study unit operations in the pharmaceutical manufacturing of solid dosage forms. The pharmaceutical materials investigated were anhydrous caffeine, lactose monohydrate and micro- crystalline cellulose (MCC). At the macroscopic level, blending experiments …
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Sierra Nevada Brewery Design Project
… research and calculations were done on the unit operations necessary for brewery design and waste treatment. A full economic and profitability analysis was performed on both processes. Alternative cases for fermentation were considered. An analytical fermentation model was produced to show …
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