Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Unfolding Energy Landscape"”.
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Towards Understanding Membrane Protein Folding and Stability with Solid-State NMR and Hydrogen/Deuterium Exchange
… site-specifically follow the thermally induced unfolding events of MPs in their lipid environment. We first employed this methodology to obtain an atomistic description of the thermally induced unfolding pathway of a retinal-binding photoreceptor Anabaena Sensory Rhodopsin (ASR). The pathway is …
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Investigation of structural dynamics and the function of membrane proteins with computational techniques
… glutamate transporters. These extensive free energy calculations allowed us to capture, in atomic details, the forward transition cycle and specific intermediates which might play an important role in designing novel therapeutics against various neurological disorders. We applied our protocol …