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Showing 1 to 1 of 1 for “"Unfolded Protein Stress Response"”.
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Mitochondrial Unfolded Protein Response Regulator Atf5 In Mitochondrial Targeted Therapies In Aml
<p>Mitochondrial unfolded protein response (UPR<sup>mt</sup>) is an adaptive transcriptional response induced by damaged proteins accumulated in mitochondria. UPR<sup>mt</sup> signaling involves induction of mitochondrial specific chaperones and proteases such as HSP60, LonP1 and ClpP, aiding in …