Global ETD Search
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Showing 1 to 1 of 1 for “"Unfolded Protein Response, Autophagy, ER stress, Acute Promyelocytic Leukemia, Apoptosis, N-CoR"”.
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Role of Abberant Proteolysis in the Pathogenesis of APL
Acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML), is caused by PML-RARN1, a fusion protein resulting from chromosomal translocation involving the promyelocytic leukemia (PML) and the retinoic acid receptor N1 (RARN1) genes. PML-RARN1 promotes misfolding of nuclear …