Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Ubiquitin-Activating Enzymes"”.
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Mechanistic Studies of the Activation of Ubiquitin-Conjugating Enzymes by Ring-Type Ubiquitin Ligases
Ubiquitination, modification with ubiquitin, is a post-translational regulation of proteins in eukaryotes. Ubiquitin-activating enzymes (E1) activate ubiquitin and form thioester linkages with ubiquitin, which are then transferred onto ubiquitin-conjugating enzymes (E2). Ubiquitin-conjugating …
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Identification and Characterization of a New E1 That Activates Ubiquitin and FAT10
Ubiquitination is one of many post-translational modifications in eukaryotes. Three enzymes (E1, E2, and E3) are involved in conjugating ubiquitin to protein substrates. I identified a novel E1-like protein, E1-L2, which is homologous to the ubiquitin E1 and another E1 involved in the activation of …
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Regulation of The Heat Shock Response By Thiol-Reactive Compounds In The Yeast Saccharomyces Cerevisiae
… the protein quality control system such as the ubiquitin-proteasome system (UPS). To address this hypothesis, β-galactosidase reporter fusions were used as model substrates to demonstrate that thiol-reactive compounds do not inhibit ubiquitin activating enzymes (E1) or proteasome activity. …
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Non-lysosomal protein degrading systems in chicken skeletal muscle
… an attempt to understand the roles played by the ubiquitin-dependent and calpain pathways in protein degradation in chicken skeletal muscles, biochemical studies were conducted on components of these two systems as well as their potential endogenous and exogenous substrates. ATP- and …
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Non-lysosomal protein degrading systems in chicken skeleton muscle
… an attempt to understand the roles played by the ubiquitin-dependent and calpain pathways in protein degradation in chicken skeletal muscles, biochemical studies were conducted on components of these two systems as well as their potential endogenous and exogenous substrates. ATP- and ubiquity …