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Showing 1 to 1 of 1 for “"Ube2N/Ube2V2"”.
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Structural Insights into TRIM21 Ubiquitination Mechanisms
… that TRIM21 requires the E2 enzymes Ube2W and Ube2N/Ube2V2 to build K63-linked ubiquitin chains and drive anti-viral function. My work reveals how TRIM21 facilitates ubiquitin transfer and differentiates Ube2N from other closely related enzymes. A tri-ionic motif allows TRIM21 to wrap an …