Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 309 for “"UTR"”.
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UTR prediction programs for trypanosoma brucei
… known as untranslated regions of sequence or UTRs. These regions tend to exhibit less cross-species conservation than do coding sequences. There are many software packages available today for use in determining UTRs, most of which are only available for use by not-for-profit organizations such …
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Mammalian gene regulation through the 3' UTR
The untranslated region (UTR) at the 30 end of a mammalian mRNA is typically rich with regulatory motifs that influence the stability, localization, translation and other properties of the message. We explored two classes of motifs, microRNA (miRNA) complementary sites and cleavage and …
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Physiological performance characteristics of Universal Tennis Rating (UTR)
1 PDF file (viii, 48 pages)
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Translational Regulation in the 5′UTR of Enteroviruses
The genus Enterovirus consists of a large group of positive-sense RNA viruses, with over 100 serotypes known to be human pathogens. Disease phenotype in humans ranges from sub- clinical to acute flaccid paralysis and treatment options for infection with these viruses are limited, with only few …
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Regulation and Function of the Dscam1 Extended 3' UTR mRNA
… of APA. Specific function of these longer 3' UTR transcripts are largely unknown; however, because the 3' UTR can regulate transcript stability, translational efficiency, and localization, it is plausible that 3' UTR switching in nervous tissues may serve important biological functions. We …
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Characterization of 5 UTR splicing and the CGI in HIV-2 RNA
… genomic RNA. Two elements of interest are the 5 UTR intron and the proposed long distance base pairing interaction between the C-box and G-box termed the CGI. This research focuses on the effects of 5 UTR splicing and the CGI in HIV-2 translation and replication. The central hypothesis is that …
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Characterization of 5 UTR splicing and the CGI in HIV-2 RNA
… genomic RNA. Two elements of interest are the 5 UTR intron and the proposed long distance base pairing interaction between the C-box and G-box termed the CGI. This research focuses on the effects of 5 UTR splicing and the CGI in HIV-2 translation and replication. The central hypothesis is that …
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Uranium dioxide and urania-thoria fuel cores for the UTR-10 reactor
… cores for the Virginia Polytechnic Institute UTR-10 Reactor.
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A temperature study of the V.P.I. training and research reactor (UTR-10)
… heat from the core of the reactor. In the V.P.I. UTR-10, the heat is removed from the fuel plates by the light water moderator-coolant which is pumped between the plates. The maximum temperature which the fuel will attain is determined by the coolant temperature, the coolant flow rate, and the …
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Functional analyses of ζ-crystallin binding to the 3'-UTR of glutaminase (GA) mRNA
… established that the 3'-untranslated regions (3'-UTR) of the 4.5 kb GA mRNA contains the 8-base adenylate-uridylate (AU) sequence that functions as a pH-responsive element (pHRE) The pHRE binds (ζ-crystallin /NADPH:quinone reductase (ζ-crystallin) with high affinity and specificity. Analysis of …
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Deconvoluting Cell-Type Specific 3'UTR Isoform Expression in the Adult and Developing Cerebellum
<p>Alternative polyadenylation has been implicated in the regulation of mRNA translation and stability, as well as mRNA and protein localization. However, it is unclear to what extent alternative polyadenylation regulates these processes uniquely in specific cell types. Using a newly developed …
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Analysis of cis-acting expression determinants of the tobacco psbA 5’UTR in vivo
… to be regulated via its 5’- untranslated region (UTR). Some cis-acting elements within this 5’UTR and the correlated trans-acting factors have been defined in Chlamydomonas. However, no in vivo evidence with respect to the cis-acting elements of the psbA 5’UTR has been so far achieved in higher …
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Zur Bedeutung der polyTC-Motive in den Promotoren und 5‘-UTR-Bereichen konstitutiv exprimierter Pflanzengene
… (Beta vulgaris) besitzt im Promotor und der 5’UTR je eine Polypyrimidinbox. Solche Motive aus sich häufenden TC-Alternierungen sind in pflanzlichen Promotoren und 5’UTRs ein häufig auftretendes Motiv mit bislang weitgehend ungeklärter Funktion. Am Beispiel des Promotors Y11037 des konstitutiv …
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Characterisation of the 3'-UTR of the COL5A1 gene: implication for musculoskeletal soft tissue injuries
… C/T) within the 3'-untranslated region (UTR) of COL5A1 is associated with chronic Achilles tendinopathy (TEN) and other soft tissue injuries as well as exercise-related phenotypes. These phenotypes are directly or indirectly associated with the mechanical properties of musculoskeletal …
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Regulation of mRNA expression through 3’ UTR sequences of IL6 gene in amino acid-deprived HeLa cells
… cytokines. Here, it was investigated whether 3’UTR of IL6 mRNA played a role in IL6 induction through cellular stress responses. In the studies with GFP-reporter containing 3’UTR of IL6 mRNA, it was elucidated that 3’UTR contributed to increase of IL6 mRNA after amino acid-starvation, and its …
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Characterization of the instability elements present within the 3' UTR of the glutaminase mRNA in WKPT kidney cells
During metabolic acidosis, the level of glutaminase (GA) is increased 8-fold within the renal proximal convoluted tubule. This adaptation contributes to the ability of the kidney to generate NH4+ and HCO3- ions from glutamine to facilitate the excretion of acids and partially restore acid-base …
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