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Showing 1 to 2 of 2 for “"USP37"”.

  1. Deubiquitinating Enzymes Promote Cancer Progression and Metastasis Via Regulating Protein Stability

    Xiao, Zhenna, <p>0000-0002-7321-5593</p>2020

    … apoptosis and chemotherapy. Here we identified USP37 as a SNAI1 deubiquitinase. USP37 binds, deubiquitinates, and stabilizes SNAI1. Overexpression of the wild-type USP37, but not its catalytically inactive mutant C350S, promotes cancer cell migration. Depletion of USP37 inhibits cancer cell …

    uthsc Repository record

  2. Interrogating DNA replication stress and DNA damage responses via phenotypic and functional CRISPR/Cas9 screens

    Pilger, DomenicUniversity of Cambridge2021

    … provide evidence for the deubiquitinating enzyme USP37 regulating RPA loading and DNA repair during DNA replication.

    cambridge Repository record