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Showing 1 to 2 of 2 for “"USP17"”.

  1. The role of USP17 in lysosome trafficking and lysosomal function

    … regulation of most complex cellular processes. USP17, a member of the ubiquitin specific protease (USP) family of deubiquitinases, has been shown to be required for cell cycle progression, cell motility, endocytosis and our previous studies have preliminarily shown it is required for lysosome …

    qu-belfast Repository record for The role of USP17 in lysosome trafficking and lysosomal function (opens in a new tab)

  2. Locus-specific proteomics identifies novel repressors of Epstein-Barr virus reactivation

    … massive upregulation of the human deubiquitinase USP17. USP17 upregulation was driven by EBV lytic proteins and overexpression of USP17 was associated with deubiquitination of H2AK119Ub. The complexity of the USP17 gene locus, comprising at least 32 copies, made its depletion very challenging. …

    cambridge Repository record for Locus-specific proteomics identifies novel repressors of Epstein-Barr virus reactivation (opens in a new tab)