Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 24 for “"UREMIC SYNDROME"”.
-
Genetic Factors Associated with Anti-Factor H Autoantibodies in Atypical Hemolytic Uremic Syndrome (aHUS)
Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy characterized by renal failure and determined by genetic and acquired defects of alternative pathway (AP) of the complement system. Autoantibodies against factor H (anti-FHs), a regulator of the AP, were reported …
-
The hemolytic uremic syndrome in childhood. A focus on Shiga toxin and its consequences
Contains fulltext : 250224.pdf (Publisher’s version ) (Open Access)
-
Genetic and Chemical Genetic Approaches to Shiga Toxin Inhibition
… place patients at risk of developing hemolytic uremic syndrome, a toxemic condition characterized by hemolytic anemia, thrombocytopenia, and acute renal failure. Though hemolytic uremic syndrome remains the leading cause of acute renal failure in children under the age of 5, treatment of this …
-
Investigation of Phosphatidylinositols and Phosphoinositides Using Matrix- Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
… various diseases, including atypical hemolytic uremic syndrome (aHUS), necessitating a deeper understanding of their spatial distribution and abundance. Given the low concentration of PIs and PIPs, the study aimed to optimize MALDI-MSI for their detection. Thus, various chemical matrices …
-
ΗΛΕΚΤΡΟΚΑΡΔΙΟΓΡΑΦΙΚΑΙ ΑΛΛΟΙΩΣΕΙΣ ΚΑΙ ΠΡΟΔΙΑΘΕΣΙΚΟΙ ΠΑΡΑΓΟΝΤΕΣ ΣΤΕΦΑΝΙΑΙΑΣ ΝΟΣΟΥ ΕΠΙ ΝΕΦΡΟΠΑΘΩΝ
… FAILURE AND THE BIOCHEMICAL PARAMETERSOF THE UREMIC SYNDROME WERE STUDIED. FROM THE TOTAL OF 566 PATIENTS STUDIED, 406 WERE ON CONSERVATIVE TREATMENT (GROUP A) AND 160 WERE ON CHRONIC HEMODIALYSIS (GROUP B). THE RESULTS ARE AS FOLLOWS: DURATION OF RENAL FAILURE: 34,57 +-39,25 MONTHS. DURATION …
-
Assembly of the O Antigen in the Highly Pathogenic Escherichia Coli Serotype O104:H4
… that causes severe bloody diarrhea and hemolytic-uremic syndrome, which can lead to kidney failure and death. Lipopolysaccharides (LPS) are important virulence factors in Gram-negative bacteria and our goal is to understand the enzymes and mechanisms involved in the assembly of the outer O …
-
Jautienoje aptiktų Šiga toksiną išskiriančių Escherichia coli identifikavimas ir genominė analizė /
… diarrhea to hemorrhagic colitis (HC), hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). Cattle are considered the primary source of STEC and humans usually become infected by consuming contaminated food or water, through the environment or by direct contact with …
-
Gut Microbiome Dysbiosis Exacerbates Malaria Severity in Ugandan Children
… to intravascular hemolysis through hemolytic uremic syndrome. This study identified gut dysbiosis during SM that associates with worse clinical complications and post-discharge mortality in a cohort of Ugandan children, suggesting that the gut microbiome may contribute to SM pathogenesis in …
-
The Characterization of Quorum Sensing E. Coli Regulators E,F, and G (Qse EFG) and Their Role in Pathogenesis
… colitis and life-threatening hemolytic uremic syndrome (HUS) worldwide. EHEC colonizes the large intestine and adheres to intestinal epithelial cells by forming attaching and effacing lesions (AE). These lesions result in the rearrangement of the actin cytoskeleton to pedestal-like …
-
Effects of low molecular weight compounds on growth, virulence gene expression and cytotoxic activity of Shiga toxin-producing Escherichia coli O157:H7
… with hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS), and are the leading cause of acute renal failure in children. A series of novel low molecular weight chemical compound (LMWC) capable of inhibiting various virulence gene expressions in E. coli O157:H7 has been identified, …
-
Studies of EHEC and the complement system in renal diseases
… course of specific renal diseases hemolytic uremic syndrome (HUS) and dense deposit disease (DDD). HUS may be associated with infection caused by Enterohemorrhagic Escherichia coli (EHEC) or with complement dysfunction due to complement mutations or auto-antibodies (atypical HUS, aHUS). EHEC …
-
Clinical Presentation and Histopathological Description of the Spectrum of Renal Diseases in HIV Infected Adults Presenting With Renal Insufficiency at the University Teaching Hospital,Lusaka Zambia
… and chronic interstitial nephritis, haemolytic uremic syndrome and many others. Objective: To determine the clinical presentation and histopathological description of the spectrum of renal diseases in HIV infected adult patients presenting with renal insufficiency at the University Teaching …
-
Clinical Presentation and Histopathological Description of the Spectrum of Renal Diseases in HIV Infected Adults Presenting With Renal Insufficiency at the University Teaching Hospital,Lusaka Zambia
… and chronic interstitial nephritis, haemolytic uremic syndrome and many others. Objective: To determine the clinical presentation and histopathological description of the spectrum of renal diseases in HIV infected adult patients presenting with renal insufficiency at the University Teaching …
-
E. COLI STEC MONITORING IN A ONE HEALTH APPROACH.
… severe gastrointestinal diseases and hemolytic uremic syndrome (HUS), this research aims to provide a comprehensive understanding of the pathogen's dynamics across human, animal, and environmental interfaces. The introduction outlines the historical context of E. coli discovery and its …
-
Detection of food contaminants by SERS and nanopore technology
… hemorrhagic colitis (HC), the hemolytic-uremic syndrome (HUS). Thus, quick and efficient detection methods of this pathogen are crucial in the food safety and diagnosis. Conventional methods, such as plate counting and PCR ensure high accuracy yet are time-consuming and labor intensive. …
-
Post-Transcriptional Regulation of Virulence Genes by GlmY and GlmZ in Enterohemorrhagic E. Coli
… a major cause of foodborne illness and hemolytic uremic syndrome (HUS) throughout the world. One of the major virulence factors in this pathogen is a type III secretion system (T3SS) encoded by the locus of enterocyte effacement (LEE). EHEC uses this proteinaceous needle to inject effector …
-
Characterization of OmpT: An outer membrane vesicle protease Escherichia coli that attenuates blood coagulation.
… renal failure, bloody diarrhoea, hemolytic uremic syndrome, thrombocytopenia, hemolytic anemia and other systemic problems. E. coli O157:H7 is responsible for outbreaks of Enterohemorrhaghic E. coli infections and causes significant mortality and morbidity globally. Factor V (Mr-330,00Da) is …
-
Genetic, molecular and functional analyses of factor I - an inhibitor of the complement system
… in complete FI deficient- and atypical hemolytic uremic syndrome (aHUS) patients. The mutations were introduced in recombinantly expressed proteins, purified and analyzed in functional assays. The mutations are homozygous or compound heterozygous in patients with complete FI deficiency and the …
-
The Functional Characterization of QSEC a Bacterial Adrenergic Receptor and the LuxR Homologue SDIA in EHEC
… of hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The histidine sensor kinase QseC is an inner membrane adrenergic receptor which responds to the bacterial signal autoinducer-3 (AI-3) and the host signals epinephrine and norepinephrine. EHEC senses these signals in the gut in …
-
Characterization of Complement C3 Dysregulation Predisposing to Two Human Disease States
… to a secondary C3 deficiency. Atypical hemolytic uremic syndrome: aHUS) is a thrombotic microangiopathy that primarily affects the kidneys. This disease is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Heterozygous mutations in the regulatory …
Page 1 of 2