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Showing 1 to 20 of 23 for “"UPTAKE AND METABOLISM"”.
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The Uptake and Metabolism of Potassium-Cyanide-(carbon-14-Labeled) and Acetonitrile-1-(carbon-14-Labeled) in Plant Tissues
Made available in DSpace on 2015-05-12T17:04:09Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 0019876.PDF: 5234004 bytes, checksum: f6e8593d4331da04fd35560b8f1db7da (MD5) Previous issue date: 1956
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ELEMENTAL COMPOSITION AND NUTRIENT EFFECT ON THE UPTAKE AND METABOLISM OF DISSOLVED ORGANIC CARBON BY BACTERIA FROM A TEMPERATE REGION RIVER
Rivers are arteries that connect land and sea, and provide a conduit and reactor for allochthonous and autochthonous organic carbon sources (OC) delivered to the coastal ocean. In comparison to marine waters, inland waters quantitatively represent only a fraction of the marine system; however, …
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Uptake and Metabolism of 5’-Amp In The Erythrocyte Play Key Roles In The 5’-Amp Induced Model of Deep Hypometabolism
<p>UPTAKE AND METABOLISM OF 5’-AMP IN THE ERYTHROCYTE PLAY KEY ROLES IN THE 5’-AMP INDUCED MODEL OF DEEP HYPOMETABOLISM</p> <p>Publication No. ________</p> <p>Isadora Susan Daniels, B.A.</p> <p>Supervisory Professor: Cheng Chi Lee, Ph.D.</p> <p>Mechanisms that initiate and control the natural …
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An in vitro study of the effects of free fatty acids on insulin mediated glucose uptake and metabolism by myocytes and fibroblast derived adipocytes
… consumption of a westernized diet, rich in fats and sugar, is associated with hyperlipidemia, obesity and development of T2D. Skeletal muscle and adipose tissues are the major tissues involved with post-prandial peripheral glucose disposal in response to insulin. Insulin resistance reduces the …
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Examination of 2,4-D tolerance in perennial Glycine species and the involvement of cytochrome P-450 as a tolerance mechanism
… acid) were expressed at the cell and whole plant level by several accessions of wild perennial Glycine species. Heterotrophic cell suspension cultures of soybean (Glycine max (L.) Merr.) and four perennial Glycine accessions were used to investigate ($\sp{14}$C) 2,4-D uptake and …
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Role of Lipolysis and Lipogenesis in the Development of Diet-Induced Obesity
… of the American adult population overweight and one-quarter considered obese. This alarming trend has led researchers to determine potential causative factors of excess weight gain in humans. However, it is difficult to discern whether perturbations that result in obesity are the cause or …
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Characterization of GSDMD as a Positive Regulator of Breast Cancer Cell Proliferation and Mammary Tumorigenesis
… (BC) is the most frequently diagnosed cancer and is classified into subtypes based on the presence or absence of hormone receptors. These molecular markers can be exploited for targeted therapy, which has led to substantial improvements in BC prognosis and survival rates. Yet, three key …
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Measuring Single Cell Responses to Lapatinib In A Heterogeneous Population
<p>Cancer is notonedisease butasaga of diseases and is the outcome of disturbed homeostasis in the normal cells due to the deregulation of its genetic makeup. With advent of technologies thatallowdetailed molecular characterizationoftumors, targeted therapies have emerged as a more promising and …
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FDG-PET in Cervical Cancer - Translational Studies
… FDG-PET enables non-invasive studies of glucose metabolism. Cancer cells show an increased glucose uptake and metabolism that can be visualised and further analysed. The aims of this thesis were to evaluate FDG-PET in the clinical management of cervical cancer and to experimentally investigate …
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Assessing Availability and Utilization of Essential Amino Acids in Dairy Cattle Using Stable Isotope Based Approach
Determining the AA availability and metabolism in ruminant is a big challenge due to the rumen fermentation and complicated post absorption utilization. Current techniques used for direct determination of AA absorption and metabolism are laborious and expensive with large variation. The objectives …
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Treating type 2 diabetes through insulin resistance
… 2 diabetes is an insidious disorder, with micro and/or macrovascular and nervous damage occurring in many patients before diagnosis. This damage is caused by hyperglycaemia and the diverse effects of insulin resistance. Obesity, in particular central obesity, is a strong pre-disposing factor for …
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Correlation of Heparan Sulfate Proteoglycan Structure and Metabolism With the Regulation of Cell Division
… several heparan sulfate (HS) chains. Growing and confluent cultures of a rat hepatocyte cell line were labeled with $\sp{35}$SO$\sb4\sp{2-}$ and the HS in the culture medium, the pericellular matrix, the nucleus, the outer nuclear membrane, and the remaining cytoplasmic pool was purified by …
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Effects of experimentally-altered hydrology on ecosystem function in headwater streams
… are important integrators of terrestrial and aquatic systems and their function depends greatly on water availability. In the southern Appalachians, models of future climate change predict alterations to the timing and intensity of storms such that most precipitation may be relegated to …
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The significance of OATP and CYP450 in statin-flavonoid interactions
… by drug-drug interactions between statins and conventional medicines that may inhibit metabolic pathways important to statin clearance. Though drug-drug interactions are well characterised with statins, there has been little investigation into herb-drug interactions with statins. Herbal …
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Biological role of conceptus derived factors during early pregnancy in ruminants
… in development, or occurs later in gestation and is characterized by endometrial dysfunction, or asynchrony between the conceptus (embryo and trophectoderm) and uterus. During early pregnancy in sheep, endometrial functions are primarily regulated by ovarian progesterone (P4) and interferon …
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Oxysterols in Neurodegeneration and the Influence of Presynaptic α-Synuclein Phosphorylation
… diseases such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) are marked by progressive neuronal dysfunction, often driven by protein misfolding and chronic cellular stress. Among the emerging contributors to these pathologies is disrupted cholesterol metabolism, particularly the …
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Developing and utilizing a robust mass spectrometry-based approach to study glucose metabolism and transport in the lens
… is an essential component of the ocular system and has a high metabolic demand. However, the delivery of energy sources such as glucose and waste removal cannot occur via the vasculature as this would obstruct the path of light through the lens. Thus, the lens requires a highly developed glucose …
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Characterization of the effect of nitrogen deficiency on above-ground plant phenotypes in relation to root complexity in maize
… an essential plant nutrient in maize production, and if considering only natural sources, is often the limiting factor world-wide in terms of a plant’s grain yield. For this reason, many farmers around the world supplement available soil N with synthetic man-made forms. Years of over-application …
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Therapeutic Effects and Targeted Delivery of Eupenifeldin in Castration-Resistant Prostate Cancer
… challenge, as it often fails to respond to standard treatments such as taxane-based chemotherapies, androgen receptor pathway inhibitors, and radioligand-based approaches1–4. Despite these treatments, CRPC remains incurable, and novel therapeutic strategies are urgently needed1,5. This thesis …
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The intestinal absorption of n-3 and n-6 polyunsaturated fatty acids: proposed mechanisms from studies using human Caco-2 cells.
… by which specific dietary fatty acids, the n-3 and n-6 polyunsaturated fatty acids (PUFAs), enter the intestinal absorptive cell. The intake of these particular fats and the ratio of n-6/n-3 PUFAs have been correlated with the development/regression of various diseases -like arteriosclerosis, …
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