Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"UNC-44"”.
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Regulation of Polarized Protein Transport to Axons, Dendrites, and Sensory Cilia in Caeborhabditis Elegans Neurons
… between these domains are critical for neuronal function, and are a result of asymmetric trafficking of a large number of cellular components including ion channels, neurotransmitter receptors, synaptic vesicles, and signaling proteins. Yet, despite the significance of asymmetric protein transport …
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Defects in protein trafficking affect expression of GPCRs in C. elegans
… of other neurons. Mutations in six genes (tba-1, unc-14, unc-33, unc-44, unc-51, unc-119) known to disrupt axon outgrowth were found to eliminate expression of sra-6::gfp and egl-47::gfp in PVQ soon after hatching. Expression of sra-6::gfp was high in embryos and newly hatched L1 larvae, yet the …
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A Developmental Pathway for Epithelial-to-Motoneuron Transformation in C. Elegans
… factors Olig2 and Ngn2, leading to adherens junction loss, delamination from the epithelium, cell migration, and neuronal maturation. A similar sequence of events characterizes formation of pancreatic insulin-secreting β-cells, which are innervated and express genes also active in motoneurons. …