Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"ULK"”.
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Dissecting the Physiological Roles of ULK1/2 in the Mouse Brain
<p>Mammalian UNC-51–like kinases 1 and 2 (ULK1 and ULK2), Caenorhabditis elegans UNC-51 and Drosophila melanogaster Atg1 are redundant serine/threonine kinases that regulate flux through the autophagy pathway in response to various types of cellular stress. C. elegans UNC-51 and D. melanogaster …
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Algebraic level sets for CAD/CAE integration and moving boundary problems
… the risk of fracture in the ultra low-k (ULK) dies due to copper (Cu) wirebonding process. Maximum damage induced in the interlayer dielectric (ILD) stack during the process steps is proposed as an indicator of the reliability risk. Numerical techniques based on enriched isogeometric …
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Modulation of Mitochondrial Respiration and Metabolic Signalling in Skeletal Muscle by Caveolin-3
… targets of mTORC1 that include S6K1, 4EBP1 and ULK-1. The reduced activation of the mTORC1/S6K1 axis is also associated with a marked decline in myocellular protein synthesis and a reduction in cellular proliferation. The results presented in this thesis indicate that Cav3 is a novel regulator …
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Implementation of a Conrad Probe on a Boundary Layer Measurement System
This thesis presents the design, calibration, and performance evaluation of a type of two-hole pressure probe anemometer known as a Conrad probe, as well as its subsequent implementation on an autonomous, compact boundary layer measurement device and its first application for subsonic in-flight …
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Study of PECVD Films Containing Flourine and Carbon and Diamond Like Carbon Films for Ultra Low Dielectric Constant Interlayer Dielectric Applications
… (5% by volume in Helium) as precursors. The bulk dielectric constant (k) of the film was optimized from 2.0 / 2.2 to 1.8 / 1.91 as-deposited and after heat treatment. Films, with highly promising k-values but discarded for failing to meet shrinkage rate requirements were salvaged by utilizing …
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Mitophagy-Mediated Regulation of ROS Homeostasis During HSC Activation Contributes to Cell Fate
… that HSCs lacking the mammalian Atg1 homologues, ULK1 and ULK2, have a defect in mitophagy but no significant impairment in basal flux through the autophagy pathways to explore the role of mitophagy in HSCs. Despite the comparable increase in mitochondrial content in HSCs lacking Ulk1/2 or Atg7 …