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Showing 1 to 3 of 3 for “"UHDR"”.
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Radiation biophysical modeling of the FLASH effect: from mechanistic understanding towards clinical endpoint prediction
Background Ultra-High Dose Rate (UHDR) or, commonly, FLASH irradiation is a novel dose-delivery technique based on fast beam release, with typically a total irradiation time < 100 ms and a total mean dose rate > 40 Gy/s for a single dose, usually higher than 10 Gy. Experimentally, compared to …
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Insights into the radiation Chemistry of FLASH Radiation Therapy
… delivers radiation at ultra-high dose rates (UHDR) and has shown consistent normal tissue sparing while preserving tumor control compared to conventional RT—a phenomenon termed the FLASH effect. Despite promising results, the mechanisms behind the FLASH effect remain unclear. Many hypotheses …
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Facilitating the Clinical Translation of Flash Radiotherapy Through Dosimetry Development and Beam Parameter Optimization
… Recently, ultra-high dose-rate (UHDR) RT (mean dose rates ≥40 Gy/s for a total duration of ≤200 ms) has been reported to selectively spare normal tissues and organs while maintaining an isoeffective tumoricidal effect compared to conventional (CONV) dose rate RT in a variety of …