Global ETD Search
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Showing 1 to 2 of 2 for “"UGT2B7"”.
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Studies investigating the impact of select genotypes on the pharmacological effect of fenofibrate
… variability. We identified a genetic variation, UGT2B7 A-327G, harbored in a key metabolizing gene of fenofibrate. It was the source of a 17% differences in the percent-change of triglycerides, post-fenofibrate treatment, between UGT2B7 A-327G genotype groups. We hypothesized that this lipid …
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Pharmacogenomics of sickle cell disease therapeutics: pain and drug metabolism associated gene variants and hydroxyurea-induced post-transcriptional expression of miRNAs
… P = 0·031; ADRB2-rs1042713; P < 0·001; UGT2B7-rs7438135, P = 0·037). The 3·7 kb HBA1/HBA2 deletion correlated with increased VOC (P = 0·002). HbF-promoting loci variants correlated with decreased hospitalisation (BCL11A-rs4671393, P = 0·026; HBS1L-MYB-rs28384513, P = 0·01). APOL1 G1/G2 …