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Showing 1 to 20 of 177 for “"UDP"”.

  1. Structural and mechanistic studies on eukaryotic UDP-galactopyranose mutases

    Oppenheimer, Michelle LynnVirginia Tech2012

    … drug design. Galf is synthesized by the enzyme UDP-galactopyranose mutase (UGM), which converts UDP-galactopyranose (UDP-Galp) to UDP-galactofuranose (UDP-Galf). Solving the mechanism and structure of UGMs will aid in the development of specific inhibitors against these enzymes. Herein we …

    vt Repository record

  2. Uridinediphosphate-glucuronosyltransferase (UDP-GT) Ontogeny and PCB Effects in Galliform Birds

    McCleary, Ryan J. R.Virginia Tech2001

    Hepatic UDP-GTs are partly responsible for metabolism of the thyroid hormone, thyroxine (T4), in mammals, but little is known of UDP-GT activity in birds. To determine the ontogenic pattern of UDP-GT activity in precocial birds, we measured activity in Japanese quail (Coturnix japonica) liver at …

    vt Repository record

  3. Investigating the role of the UDP-galactose transporter SLC35A2 in the regulation of HIF signalling

    Greef, BasmaUniversity of Cambridge2023

    … of HIF is of intense interest. The Golgi UDP-galactose transporter SLC35A2 was identified by the Ashcroft group as a novel regulator of HIF-α, and CHO cells that had lost SLC35A2 exhibited elevated HIF-α protein in normoxia. It is known that the absence of SLC35A2 in the Golgi leads to …

    cambridge Repository record

  4. Structural and Functional Characterization of B. Anthracis Udp-Glcnac 2-Epimerase and Salmonella Secreted Effector I

    Bhaskaran, Shyam

    … study of the Bacillus anthracis cell-wall enzyme UDP-GlcNAc 2-Epimerase and the Salmonella secreted virulence effector SseI. UDP-GlcNAc 2-Epimerase is an essential B. anthracis enzyme required for formation of the peptidoglycan cell wall precursor UDP-ManAc. We have solved the epimerase's crystal …

    rockefeller Repository record

  5. Elucidation of the pathways responsible for the biosynthesis of UDP-N,N'-diacetylbacillosamine in bacterial pathogens

    Morrison, Michael JamesMassachusetts Institute of Technology2014

    … pathway responsible for the biosynthesis of the UDP-diNAcBac nucleotide sugar in Neisseria gonorrhoeae and Acinetobacter baumannii. UDP-diNAcBac is biosynthesized from UDP-N-acetylglucosamine through the action of a dehydratase, aminotransferase, and acetyltransferase. Specifically, these enzymes …

    mit Repository record

  6. Investigating the role of UDP-<i>N</i>-acetylhexosamine pyrophosphorylases in regulating <i>O</i>-GlcNAcylation in human disease

    Chen, XipingUniversity of Dundee2021

    … action of OGT relies on the steady supply of UDP-GlcNAc, the end product of the hexosamine biosynthetic pathway, synthesized by UDP-N-acetylhexosamine pyrophosphorylase (UAP1). Therefore, I considered whether <i>UAP1</i> gene mutations would phenocopy OGT-CDG mutations. A de novo heterozygous …

    dundee Repository record

  7. User Datagram Protocol with Congestion Control

    Cox, Spencer L.2006

    … gathering and disseminating information. TCP and UDP are the transport layer protocols responsible for transit of nearly all Internet communications. Due to the growth of real-time audio and video applications, UDP is being used more frequently as a transport protocol. As UDP traffic increases …

    byu Repository record

  8. Error Concealment for Robust Image and Video Transmissions on the Internet

    Su, XiaoUniversity of Illinois at Urbana-Champaign2015

    … To reduce delays, we have proposed to use UDP to deliver sender-receiver based multiple-description coded images. To further improve the trade-offs between delay and quality of either TCP delivery or UDP delivery, we have investigated a combined TCP/UDP delivery that can give shorter delay …

    uiuc Repository record

  9. Development and Evaluation of the Ethernet Interface(s) for the Monitoring and Control System of a New Beamforming Radio Telescope

    Srinivasan, AbiramiVirginia Tech2010

    … interface protocol is User Datagram Protocol (UDP). An analysis of the throughput obtained through the interface using UDP is compared to that achieved using Transmission Control Protocol (TCP). It is seen that the throughput with UDP is 15\% better than with TCP, and that UDP is a better …

    vt Repository record

  10. Informe de Expediente Civil No. 01526-2013-0-1601-JR-CI-04 sobre: Ineficacia de Acto Jurídico. Informe de Expediente Concursal No. 029-2003/CCO-ODI-UDP sobre: Impugnación Acuerdo de Acreedores

    Palomino Basurto, Luciana MaríaUniversidad de Lima2021

    … de Acreedores Nº de Expediente: 029-2003/CCO-ODI-UDP. El presente expediente versa sobre distintas solicitudes de suspensión de convocatoria a una Junta de Acreedores en el marco de un Procedimiento Concursal Preventivo, así como sobre una impugnación a la instalación y adopción de acuerdos en la …

    lima Repository record

  11. Extracellular Nucleotides Induce Transient Elevation of Cytosolic Calcium in Articular Chondrocytes

    Tesseyman, Mark A.2007

    … and 82 of 147 cells, respectively). In contrast, UDP produced a modest increase of calcium in 21 of 92 cells. ATP, UTP and UDP demonstrated homologous desensitization. There was a significant reduction in response to UTP following pretreatment with ATP and vice versa. However, UDP pretreatment had …

    uwo Repository record

  12. Multipath transport for virtual private networks

    Lukaszewski, DanielMonterey, CA; Naval Postgraduate School2017

    … Protocol (TCP) or User Datagram Protocol (UDP) to establish secure communication tunnels over public Internet. Multipath TCP (MPTCP) extends TCP to allow data to be delivered over multiple network paths simultaneously. This thesis first builds a testbed and investigates the potential of …

    nps Repository record

  13. Study of the Dynamics of Retaining GT-B Fold Glycosyltransferases Using Hydrogen Deuterium Exchange Mass Spectrometry

    Karki, RameshUniversity of Alabama Libraries2023

    … uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc), dynamics decrease inboth domain halves. Identical deuterium uptake plots at the NTD with I1P or UDP-GlcNAcsuggest that UDP-GlcNAc binding creates the binding site for I1P. Surprisingly, UDP bindingresults in diminished dynamics in most …

    alabama Repository record

  14. Investigation of asparagine-linked glycosylation in archaeal and bacterial systems

    Larkin, Angelyn (Angelyn Kathryne)Massachusetts Institute of Technology2011

    … a robust synthesis of the highly modified UDP-GlcNAc(3NAc)A and thus turned to the Wbp pathway from the opportunistic pathogen Pseudomonas aeruginosa. Early genetic studies suggested that P. aeruginosa produces UDP-GlcNAc(3NAc)A as a precursor to ManNAc(3NAc)A, a carbohydrate found in the …

    mit Repository record

  15. Polychlorinated biphenyl effects on avian hepatic enzyme induction and thyroid function

    Webb, Catherine MarieVirginia Tech2006

    … uridine diphosphate-glucuronosyltransferase (UDP-GT), thereby increasing thyroxine (T4) clearance. This loss of T4 can lead to hypothyroidism. In this study, an assay was validated for measuring UDP-GT activity toward T4 in Japanese quail (Coturnix japonica). Then UDP-GT induction by Aroclor …

    vt Repository record

  16. Biochemical characterization of Cj 1123 c, a putative acetyltransferase & Cj 1319, a putative C6 dehydratase from Campylobacter jejuni.

    Demendi, Melinda2008

    … that Cjll23c is responsible for the synthesis of UDP- diacetamidobacillosamine. We also show that Cj 1123c can N-acetylate the O- glycosylation pathway intermediate, UDP-4-amino-4,6-dideoxy-AltNAc, accommodate different acyl donors and O-acetylate UDP-GlcNAc, thereby generating novel sugars. We …

    uwo Repository record

  17. Investigation of the antibacterial activity and the biosynthesis gene cluster of the peptide antibiotic feglymycin

    Rausch, Saskia2012

    … das Feglymycin die Enzyme MurA (Enopyruvyl-UDP-GlcNAc Synthase) und MurC (UDP-N-Acetyl-muramyl-L-alanin Ligase) inhibiert. In spektrophotometischen Assays mit den E. coli-Enzymen MurA und MurC konnte ein Ki-Wert von 0.33 +/- 0.04 μM für das MurC Enzym und ein Ki-Wert von 3.4 +/- 1.1 μM für …

    tu-berlin Repository record

  18. Investigating asparagine-linked protein glycosylation in eukaryotic and prokaryotic systems

    Weerapana, EranthieMassachusetts Institute of Technology2006

    … which was incorporated into UDP-bacillosamine (UDP-Bac) and undecaprenyl-pyrophosphate-bacillosamine (Und-PP-Bac), which are substrates for the Pgl enzymes. Using the synthetic UDP-Bac, the role of the PglC glycophosphoryltransferase was elucidated in vitro.

    mit Repository record

  19. Targeting final steps of sugar nucleotide biosynthetic pathway against <i>Aspergillus fumigatus</i>

    Yan, KaizhouUniversity of Dundee2021

    … synthase that synthesize β-1,3 glucan from UDP-Glc. Although inhibitors of other glycosyltransferases (e.g. chitin synthases) also exhibit antifungal activity, only echinocandins have been approved for the treatment of aspergillosis. This is due to intrinsic drawbacks of targeting …

    dundee Repository record

  20. Experimental Evaluation of Convergence Layers in Delay Tolerant Networks

    Nayak, SukantiUniversity of Houston2018

    Traditional Internet protocols like TCP/IP and UDP/IP are not designed to perform efficiently in Delay Tolerant Networks (DTN) environments that operate in environments with high delays, significant losses, and intermittent connectivity. DTN uses the Bundle Protocol (BP) in the Bundle layer for …

    houston Repository record

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